DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and ikzf2

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_017213106.1	Gene:	ikzf2 / 100150224	ZFINID:	ZDB-GENE-100922-169	Length:	499	Species:	Danio rerio

Alignment Length:	303	Identity:	70/303 - (23%)
Similarity:	113/303 - (37%)	Gaps:	76/303 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 EASSG----SGHHPVKKRNSQQMTKCQKCNGSGVVLVGQHSHASHSGVGGSVKQSVTVKTECLSC 358
            |.|:|    :|....:|.||:.:........:     ||.||:..|....::||....:.|  :.
Zfish     2 ETSNGYIESNGDCSPRKENSRMLVDLSTSTPN-----GQRSHSPQSPAARTIKQEEGTEEE--TE 59

  Fly   359 RNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLA------------FAKAVYLKNH 411
            |....|....                  ||||:.     .||.            ......::|.
Zfish    60 RRAGGPDEAG------------------HSGEEG-----SGLEDPMIDSPNNLQDAGPGAEVQNE 101

  Fly   412 ARI------HTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRI 470
            ..|      :.|::|::|..||:.|:|..:|..|.:.|:||:|:.|..|.....|...|..|.|.
Zfish   102 TGIRLPNGKYNGDRPFQCNQCGVSFTQKGNLLRHIKLHTGEKPFKCPFCSYACRRRDALTGHLRT 166

  Fly   471 HTGEKPYKCEICGSAFSQAAHLKNH-AKVH-----------SGEKPYKCEICS----------AA 513
            |:..||:||..||.::.|...|:.| .:.|           |...||..|:..          ||
Zfish   167 HSVGKPHKCNYCGRSYKQRTSLEEHKERCHNYLQSVGMDSASNPGPYPGEVPKEQRPLEPAGMAA 231

  Fly   514 FADRFALKRHRGIHQKYGQTAPRQTSSDGMIVHKQEIPDMEDE 556
            |.....::|.:|...|...|.|::...:.|:  :...|::..|
Zfish   232 FDRPPVIERLQGNVGKRKSTTPQKFVGEKMV--RYSYPELNYE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	39/157 (25%)
		C2H2 Zn finger	367..387	CDD:275368	0/19 (0%)
		zf-H2C2_2	379..403	CDD:290200	6/35 (17%)
		C2H2 Zn finger	395..415	CDD:275368	4/37 (11%)
		zf-H2C2_2	407..432	CDD:290200	8/30 (27%)
		C2H2 Zn finger	423..443	CDD:275368	7/19 (37%)
		zf-H2C2_2	435..460	CDD:290200	8/24 (33%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		zf-H2C2_2	464..488	CDD:290200	10/23 (43%)
		COG5048	475..>529	CDD:227381	19/75 (25%)
		C2H2 Zn finger	479..499	CDD:275368	6/20 (30%)
		zf-H2C2_2	491..515	CDD:290200	9/45 (20%)
		C2H2 Zn finger	507..527	CDD:275368	6/29 (21%)
ikzf2	XP_017213106.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910