Protein Alignment Clamp and ZNF705G

DIOPT Version :10

• Sequence 1: NP_001014498.1
• Gene: Clamp / 35445
• FlyBaseID: FBgn0032979
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001157929.1
• Gene: ZNF705G / 100131980
• HGNCID: 37134
• Length: 300
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 90/309 - (29%)
• Similarity: 139/309 - (44%)
• Gaps: 55/309 - (17%)

  Fly   226 SMLQQSKRKGPKQVRCESCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQT 290
            :|:..||||..:.|..|:.........|..:.::.                   .||:|......
Human    22 AMMDTSKRKLYRDVMLENISHLVSLGYQISKSYII-------------------LQLEQGKELWR 67

  Fly   291 GG------TTPKREASSGSGH----HPVKKRN-SQQMTKCQ--------KCNGSGVVLVGQHSHA 336
            .|      ..|.||::....|    ||:.::: |..||...        :||.|
Human    68 EGRVFLQDQNPNRESALKKTHMISMHPITRKDASTSMTMENSLILEDPFECNDS----------- 121

  Fly   337 SHSGVGGSVKQSVTVKTECLSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLA 401
                 |....:|.|: |:||...:..||:....||.......|...||::|:..|:|:|::|..|
Human   122 -----GEDCTRSSTI-TQCLLTHSGKKPYVSKQCGKSLRNLLSTEPHKQIHTKGKSYQCNLCEKA 180

  Fly   402 FAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWN 466
            :....:|:.|...||||:||.|..|...|:|..||:.||:||:|:|||.|....|.|.:...|..
Human   181 YTNCFHLRRHKMTHTGERPYACHLCRKAFTQCSHLRRHEKTHTGQRPYKCHQYGKVFIQSFNLQR 245

  Fly   467 HRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFA 515
            |.|.|.|:|.|:|:..|.||||::..:.:..:|:||||:.|.:|..||:
Human   246 HERTHLGKKCYECDKSGKAFSQSSGFRGNKIIHTGEKPHACLLCGKAFS 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	51/138 (37%)
		C2H2 Zn finger	367..387	CDD:275368	5/19 (26%)
		C2H2 Zn finger	395..415	CDD:275368	5/19 (26%)
		zf-H2C2_2	407..432	CDD:463886	11/24 (46%)
		C2H2 Zn finger	423..443	CDD:275368	8/19 (42%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		COG5048	475..>529	CDD:227381	17/41 (41%)
		C2H2 Zn finger	479..499	CDD:275368	6/19 (32%)
		C2H2 Zn finger	507..527	CDD:275368	4/9 (44%)
ZNF705G	NP_001157929.1	KRAB	7..66	CDD:214630	11/62 (18%)
		C2H2 Zn finger	118..138	CDD:275368	9/36 (25%)
		C2H2 Zn finger	147..166	CDD:275368	5/18 (28%)
		C2H2 Zn finger	174..194	CDD:275368	5/19 (26%)
		zf-H2C2_2	186..211	CDD:463886	11/24 (46%)
		C2H2 Zn finger	202..222	CDD:275368	8/19 (42%)
		zf-H2C2_2	214..239	CDD:463886	13/24 (54%)
		C2H2 Zn finger	230..250	CDD:275368	6/19 (32%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)