DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and znf362b

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001083017.1	Gene:	znf362b / 100038768	ZFINID:	ZDB-GENE-070424-35	Length:	438	Species:	Danio rerio

Alignment Length:	292	Identity:	87/292 - (29%)
Similarity:	127/292 - (43%)	Gaps:	40/292 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 IISTTPQAQAQLQQIVAAQTGGTTPKREAS---SGSGHHPVKK-----------RNSQQMTKCQK 321
            |..|||.:.:|      .:.||.......|   ||.|...:|.           :..:...|.:.
Zfish   155 ITPTTPTSSSQ------NRLGGAASLNTISGLASGPGMEHIKSGGLVGMLGPQPKAPRGRKKIKA 213

  Fly   322 CNGSGVVLVGQHSHASHSGVGGSVKQSVTVKTECLSCRNPSKPFSCNICGGLFSRYSSLWSHKKL 386
            .:.:|.:||     ..:..:.....|:||:..|       .|.:.|.:|.......|.:..|.|.
Zfish   214 EHNTGPLLV-----VPYPLLASGPDQAVTIAKE-------GKTYRCKVCPRTCFNKSEMQIHSKS 266

  Fly   387 HSGEKNYKCSICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVC 451
            |:..|.:||..|..:||.|.||..|.|||.|.|||.|..|...|.|..||:.|.|.|:|:|||.|
Zfish   267 HTEAKPHKCPHCSKSFANASYLAQHLRIHLGIKPYHCSYCENSFRQLSHLQQHTRIHTGDRPYKC 331

  Fly   452 GV--CDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHS--GEKPYKCEICSA 512
            ..  |:|.|.:.:.|.:|:|.|..:|||||..|..|::.:|.|:.|...|:  ..|.|.|.:|..
Zfish   332 AQPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAHAIKNAKSYCCSMCGR 396

  Fly   513 AFADRFALKRHRGIH----QKYGQTAPRQTSS 540
            |:.....|.:|...|    ......:|::|.|
Zfish   397 AYTSETYLMKHMSKHTVVEHLVSHHSPQRTES 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	55/140 (39%)
		C2H2 Zn finger	367..387	CDD:275368	5/19 (26%)
		zf-H2C2_2	379..403	CDD:290200	7/23 (30%)
		C2H2 Zn finger	395..415	CDD:275368	9/19 (47%)
		zf-H2C2_2	407..432	CDD:290200	13/24 (54%)
		C2H2 Zn finger	423..443	CDD:275368	8/19 (42%)
		zf-H2C2_2	435..460	CDD:290200	13/26 (50%)
		C2H2 Zn finger	451..471	CDD:275368	7/21 (33%)
		zf-H2C2_2	464..488	CDD:290200	11/23 (48%)
		COG5048	475..>529	CDD:227381	19/59 (32%)
		C2H2 Zn finger	479..499	CDD:275368	6/19 (32%)
		zf-H2C2_2	491..515	CDD:290200	8/25 (32%)
		C2H2 Zn finger	507..527	CDD:275368	5/19 (26%)
znf362b	NP_001083017.1	C2H2 Zn finger	247..267	CDD:275368	5/19 (26%)
		zf-H2C2_2	259..284	CDD:290200	8/24 (33%)
		C2H2 Zn finger	275..295	CDD:275368	9/19 (47%)
		zf-H2C2_2	287..312	CDD:290200	13/24 (54%)
		C2H2 Zn finger	303..323	CDD:275368	8/19 (42%)
		zf-H2C2_2	315..342	CDD:290200	13/26 (50%)
		C2H2 Zn finger	331..353	CDD:275368	7/21 (33%)
		zf-H2C2_2	345..369	CDD:290200	11/23 (48%)
		C2H2 Zn finger	361..381	CDD:275368	6/19 (32%)
		C2H2 Zn finger	395..411	CDD:275368	3/15 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000