DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6675 and Pnlip

DIOPT Version :9

Sequence 1:	NP_610132.3	Gene:	CG6675 / 35439	FlyBaseID:	FBgn0032973	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_037293.2	Gene:	Pnlip / 25702	RGDID:	3360	Length:	465	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	90/329 - (27%)
Similarity:	144/329 - (43%)	Gaps:	44/329 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 DLPFIKKIASNLN--PFGSKKLRMHFYLFKREFPECGREVDFSIERKWRHCGFNASLPTRLMIHG 159
            |.|:...|...|.  |:...::...|.|:..|..:..:::. |.....|:..|..:..||::|||
  Rat    30 DAPWSGTIDRPLKALPWSPAQINTRFLLYTNENQDNYQKIT-SDASSIRNSNFKTNRKTRIIIHG 93

  Fly   160 WMSQSRGSFNRDVKNAYLKKGEYNVIVVDWSASSANINYFSVVKLIETFGAELAQFIRNLNRQFG 224
            ::.:...::..|:.....|....|.|.|||...| ...|....:.:...|||:|..:..|....|
  Rat    94 FIDKGEENWLSDMCKNMFKVESVNCICVDWKGGS-RATYTQATQNVRVVGAEVALLVNVLKSDLG 157

  Fly   225 ADFDSMYLIGHSLGAQIAGSAGKRLKPVKVNTIFALDPAGPKFRHRGTEFRIDPSDAKYVESMHT 289
            ...|:::|||||||:.:||.||||.... :..|..||.|.|.|:....|.|:||:||::|:::||
  Rat   158 YSPDNVHLIGHSLGSHVAGEAGKRTFGA-IGRITGLDAAEPYFQGTPEEVRLDPTDAQFVDAIHT 221

  Fly   290 SA-------NFGFRRPTGSATFYPNYGAYQHSCY-------------------YLGCSHIRSYQM 328
            .|       .||..:..|...|:||.|.....|.                   :..|:|:|||:.
  Rat   222 DAAPIIPNLGFGMSQTVGHLDFFPNGGMEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKY 286

  Fly   329 FAESINSPLGFWGTPCIRDN----------GRWQCDYSQRQSIQMAGE-PSIHKEGIFYVKTSSS 382
            :.:||.:|.||.|..|...|          |...|......:.:..|: ..::::  ||:.|...
  Rat   287 YTDSIVNPTGFSGFSCSSYNVFSANKCFPCGSEGCPQMGHYADKYPGKTKELYQK--FYLNTGDK 349

  Fly   383 DPFA 386
            ..||
  Rat   350 SNFA 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6675	NP_610132.3	Pancreat_lipase_like	116..381	CDD:238363	83/301 (28%)
Pnlip	NP_037293.2	Lipase	17..352	CDD:395099	88/326 (27%)
Pnlip	NP_037293.2	PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840