DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6675 and Lipc

DIOPT Version :9

Sequence 1:	NP_610132.3	Gene:	CG6675 / 35439	FlyBaseID:	FBgn0032973	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_006510879.1	Gene:	Lipc / 15450	MGIID:	96216	Length:	526	Species:	Mus musculus

Alignment Length:	291	Identity:	81/291 - (27%)
Similarity:	120/291 - (41%)	Gaps:	57/291 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 PFGS-----------KKLRMHFYLFKREFPECGREVDFSIERKWRHCGFNASLPTRLMIHGWMSQ 163
            |||.           ||....|.||:.|....|..:........:.||||:|.|..::||||...
Mouse    30 PFGRSLGATEASKPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSGS 94

  Fly   164 SRGSFNRDVKNAYLKKG-------------------EYNVIVVDWSASSANINYFSVVKLIETFG 209
            ...:..:|..:.|...|                   ..||.:||| .|.|..:|...|:.....|
Mouse    95 ESATVGKDSDSDYQVDGLLENWIWKIVSALKSRQSQPVNVGLVDW-ISLAYQHYTIAVQNTRIVG 158

  Fly   210 AELAQFIRNLNRQFGADFDSMYLIGHSLGAQIAGSAGKRLK-PVKVNTIFALDPAGPKFRHRGTE 273
            .::|..:..|..........::|||:||||.::|.||..:. ..|:..|..||||||.|......
Mouse   159 QDVAALLLWLEESAKFSRSKVHLIGYSLGAHVSGFAGSSMDGKNKIGRITGLDPAGPMFEGTSPN 223

  Fly   274 FRIDPSDAKYVESMHT------SANFGFRRPTGSATFYPNYGAYQHSCYYL-------------- 318
            .|:.|.||.:|:::||      ..:.|.::|.....||||.|::|..|::|
Mouse   224 ERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAI 288

  Fly   319 ----GCSHIRSYQMFAESI-NSPLGFWGTPC 344
                .|:|.||..:|.:|: :|.|...|..|
Mouse   289 TQTIKCAHERSVHLFIDSLQHSDLQSIGFQC 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6675	NP_610132.3	Pancreat_lipase_like	116..381	CDD:238363	76/274 (28%)
Lipc	XP_006510879.1	Lipase	18..366	CDD:333880	81/291 (28%)
Lipc	XP_006510879.1	PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835359
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840