DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and CTDP1

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_004706.3	Gene:	CTDP1 / 9150	HGNCID:	2498	Length:	961	Species:	Homo sapiens

Alignment Length:	224	Identity:	41/224 - (18%)
Similarity:	81/224 - (36%)	Gaps:	46/224 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 LVLEIKDVLVHPD------------WTYQTG-----WRFKKRPGVDYFLQQCSRNFEIVIYTSEQ 189
            |::::...|:|..            :.:|.|     ...:.||....||::.::.:|:.::|...
Human   185 LMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGS 249

  Fly   190 GMTAFPLLDALDPYGYI-KYRLVRGATDLVEGQHTKNLDYLNRDL-----SRVIVVDCDPYTTPL 248
            .:.|..:...|||...: .:|::.....:.....|.||    |:|     |.|.::|........
Human   250 RLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNL----RNLFPCGDSMVCIIDDREDVWKF 310

  Fly   249 HPDNSLVLTKWLGNDDDVQLFDLTAFLQLIAEHQVNDVREVLRYYR--QFEDPMEQFKDNQRRLQ 311
            .| |.:.:.|::       .|..|..:......:.:..|:.:.:.|  :..:|....:|
Human   311 AP-NLITVKKYV-------YFQGTGDMNAPPGSRESQTRKKVNHSRGTEVSEPSPPVRD------ 361

  Fly   312 EQSQESIQNLPTSERQWNLTLLGRSLRGS 340
               .|.:...|..|....|....|.|.||
Human   362 ---PEGVTQAPGVEPSNGLEKPARELNGS 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	27/145 (19%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123	8/57 (14%)
CTDP1	NP_004706.3	Biotinyl_lipoyl_domains	21..111	CDD:299706
		FCP1_euk	177..323	CDD:131304	27/149 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..589		12/69 (17%)
		BRCT	636..716	CDD:237994
		FCP1_C	716..961	CDD:286402
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	730..752
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	780..949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900