DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and FCP1

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_014004.1	Gene:	FCP1 / 855320	SGDID:	S000004890	Length:	732	Species:	Saccharomyces cerevisiae

Alignment Length:	234	Identity:	56/234 - (23%)
Similarity:	84/234 - (35%)	Gaps:	72/234 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 MMEEPQMARLLPNVVPPPYIQPPYSLVLEIKDVLVHPDWTYQTGWRFKKRPGVDYFLQQCSRNFE 181
            |.::..|.|      |||                |...|.|     .|.|||:..|..:.:..||
Yeast   228 MNDDGSMLR------PPP----------------VRKCWYY-----VKVRPGLKEFFAKVAPLFE 265

  Fly   182 IVIYTSEQGMTAFPLLDALDPYG-----YIKYRLVRGATDLVEGQHTKNLDYL-NRDLSRVIVVD 240
            :.|||......|..:...:||.|     .|..|...|:..      ||:|..| ..|.|.|:|:|
Yeast   266 MHIYTMATRAYALQIAKIVDPTGELFGDRILSRDENGSLT------TKSLAKLFPTDQSMVVVID 324

  Fly   241 --------CDPYTTPLHPDNSLVLTKWLGNDDDVQLF---DLTAFLQLIAEHQVNDVREVLRYYR 294
                    | |....:.|.|..|     |..|....|   ..|..|||        .|:..:..:
Yeast   325 DRGDVWNWC-PNLIKVVPYNFFV-----GVGDINSNFLPKQSTGMLQL--------GRKTRQKSQ 375

  Fly   295 QFEDPMEQFKDNQRRLQEQSQESIQ--------NLPTSE 325
            :.::.:....||:::|||:..:.::        .|.|:|
Yeast   376 ESQELLTDIMDNEKKLQEKIDKEVKRQEEKLNHQLATAE 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	35/140 (25%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123	11/58 (19%)
FCP1	NP_014004.1	Biotinyl_lipoyl_domains	88..>112	CDD:416260
FCP1	NP_014004.1	FCP1	150..623	CDD:227517	56/234 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900