DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and ublcp1

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	XP_021324596.1	Gene:	ublcp1 / 792145	ZFINID:	ZDB-GENE-040718-3	Length:	371	Species:	Danio rerio

Alignment Length:	244	Identity:	50/244 - (20%)
Similarity:	93/244 - (38%)	Gaps:	82/244 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PEED---HRGPIEDEFSQLPWFRQYIMRMWHTLQYYEKMMEEPQMARLLPNVVPPPYIQPPYS-- 141
            ||.|   :...||:|.:::....:.:.::...::.|:  :||               :.||..
Zfish   143 PENDDVVNDFDIEEEVTEVENREENLAKIARRVKDYK--VEE---------------LNPPRPGK 190

  Fly   142 --LVLEIKDVLVHPDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTS-----------EQGMTA 193
              |||:|...|.......:||... .||.:..||.....:|:|||:::           |.|:|.
Zfish   191 RLLVLDIDYTLFDHKSCAETGHEL-MRPFLHEFLTSAYEDFDIVIWSATSMKWIDAKMKELGVTD 254

  Fly   194 FP------LLDA---------------LDPYGYI--KYRLVRGATDLVEGQHTKNLDYLNRDLSR 235
            .|      :||:               :.|.|.|  ||      ::....::|...|.:.|:..
Zfish   255 NPNYKITFMLDSAAMITVHTPKRGVVEVKPLGVIWGKY------SEFYNRKNTIMFDDIGRNFL- 312

  Fly   236 VIVVDCDPYTTPLHPDNSLVLTKW----LGNDDDVQLFDLTAFLQLIAE 280
                        ::|.|.|.:..:    |..:.|.:|:.|:.:|:.||:
Zfish   313 ------------MNPQNGLKIRPFMKAHLNREKDKELYKLSQYLKEIAK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	35/168 (21%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123	2/5 (40%)
ublcp1	XP_021324596.1	UBQ	59..130	CDD:320785
ublcp1	XP_021324596.1	HAD_IIID1	170..364	CDD:131299	44/217 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900