DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and ctdspl2a

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001071012.1	Gene:	ctdspl2a / 558181	ZFINID:	ZDB-GENE-061013-647	Length:	469	Species:	Danio rerio

Alignment Length:	229	Identity:	62/229 - (27%)
Similarity:	106/229 - (46%)	Gaps:	33/229 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PEEDHRGPIEDEFSQL-PWFRQYIMRMWHTLQYYEKMMEEPQMARLLPNVVPPPYIQPPYSLVLE 145
            |.....|..|:::... |:|         .:::...:.|| |:.| .|.:.......|.:||||:
Zfish   243 PSPPAEGTYEEDWEVFDPYF---------FIKHVPPLTEE-QLTR-KPALPLKTRSTPEFSLVLD 296

  Fly   146 IKDVLVH-----------------PDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTA 193
            :.:.|||                 .|..||...|.  ||....||::.|:.:||:::|:.:.:.|
Zfish   297 LDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRL--RPFFREFLERMSQIYEIILFTASKKVYA 359

  Fly   194 FPLLDALDP-YGYIKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLT 257
            ..||:.||| ...:::||.|.....|:|.:.|:|:.|.||||:.:::|..|........|.:.:.
Zfish   360 DKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTVIIDNSPQAFAYQLSNGIPIE 424

  Fly   258 KWLGNDDDVQLFDLTAFLQLIAEHQVNDVREVLR 291
            .|..:.:|.:|..|..||:.:.|.. .|||..:|
Zfish   425 SWFVDKNDNELLKLVPFLEKLVELN-EDVRPYIR 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	42/144 (29%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123	5/16 (31%)
ctdspl2a	NP_001071012.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..209
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	231..250		1/6 (17%)
		HIF-SF_euk	290..445	CDD:274055	46/156 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810