DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and CTDSPL2

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_057480.2	Gene:	CTDSPL2 / 51496	HGNCID:	26936	Length:	466	Species:	Homo sapiens

Alignment Length:	206	Identity:	58/206 - (28%)
Similarity:	95/206 - (46%)	Gaps:	25/206 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 WHTLQYYEKMMEEPQMARLLPNVVPPPYIQ----PPYSLVLEIKDVLVH---------------- 152
            |.....|..:...|.:.....|..|...::    |.:||||::.:.|||
Human   252 WEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVL 316

  Fly   153 -PDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDP-YGYIKYRLVRGAT 215
             .|..||...|.  ||....||::.|:.:||:::|:.:.:.|..||:.||| ...:::||.|...
Human   317 FQDVIYQVYVRL--RPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHC 379

  Fly   216 DLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGNDDDVQLFDLTAFLQLIAE 280
            ..|:|.:.|:|:.|.||||:.|::|..|........|.:.:..|..:.:|.:|..|..||:.:.|
Human   380 VCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVE 444

  Fly   281 HQVNDVREVLR 291
            .. .|||..:|
Human   445 LN-EDVRPHIR 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	43/144 (30%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123	5/16 (31%)
CTDSPL2	NP_057480.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..140
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	220..240
		HIF-SF_euk	287..448	CDD:274055	48/163 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810