DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and ctdsp2

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001006793.1	Gene:	ctdsp2 / 448497	XenbaseID:	XB-GENE-951111	Length:	271	Species:	Xenopus tropicalis

Alignment Length:	242	Identity:	62/242 - (25%)
Similarity:	111/242 - (45%)	Gaps:	38/242 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SPPKLRRIKNFYTYSVVLGSLFSIVMWAIYKLGKPEEDHRGPI-EDEFSQLPWFRQYIMRMWHTL 111
            |.||..|.::.:.      :||..:  :...:.:|......|| ::|.:..|  :..:::   .|
Frog    27 SSPKKPRSRSIFK------ALFCCL--SAQNVSRPAGSIEPPIPKEETNATP--KSDLLQ---CL 78

  Fly   112 QYYEKMMEEPQMARLLPNVVPPPYIQPPYSLVLEIKDVLVHPDW-----------------TYQT 159
            ||  :..:.|..: |||.|.|..  :....:|:::.:.|||..:                 |:|.
Frog    79 QY--QFYQIPGTS-LLPEVAPKD--KEKICMVIDLDETLVHSSFKPISNADFIVPVEIEGTTHQV 138

  Fly   160 GWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGYIKYRLVRGATDLVEGQHTK 224
              ...|||.||.||::..:.:|.|::|:.....|.|:.|.||..|..:.||.|.|....:|.:.|
Frog   139 --YVLKRPYVDEFLERMGQLYECVLFTASLAKYADPVTDLLDKSGVFRSRLFREACVFHQGCYVK 201

  Fly   225 NLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGNDDDVQLFDL 271
            :|..|.|||.:.:::|..|.:...||:|::.:..|..:..|.:|..|
Frog   202 DLSRLGRDLKKTVILDNSPASYIFHPENAVPVQSWFDDMSDTELLSL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	39/143 (27%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123
ctdsp2	NP_001006793.1	HIF-SF_euk	101..260	CDD:274055	42/150 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910