DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttm3 and tim50

DIOPT Version :9

Sequence 1:	NP_610130.1	Gene:	ttm3 / 35437	FlyBaseID:	FBgn0032971	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_595583.2	Gene:	tim50 / 2539802	PomBaseID:	SPBC17A3.01c	Length:	452	Species:	Schizosaccharomyces pombe

Alignment Length:	264	Identity:	97/264 - (36%)
Similarity:	143/264 - (54%)	Gaps:	30/264 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 GPIEDE---------FSQLPWFRQYIMRMWHTLQYYEKMMEEPQMARLLPNVVPPPYIQPPYSLV 143
            ||.|.|         :|...|:.:...|..:...||    :||...:|||:.:|.|| ..||:||
pombe   121 GPDEKELEKQYPAAGYSPSDWWNRVKARTNNFFSYY----QEPAFEKLLPDPLPEPY-NRPYTLV 180

  Fly   144 LEIKDVLVHPDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGY-IK 207
            |.:.|:|:|.:||.|.|||..||||:||||...|..:|:||:|.:...||.|::|.:|||.. |.
pombe   181 LSLDDLLIHSEWTRQHGWRTAKRPGLDYFLGYLSMYYEVVIFTRQYLATAKPIIDKIDPYHVSIS 245

  Fly   208 YRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGNDDDVQLFDLT 272
            ..|.|.::...:|:..|:|.||||||||||::|.:|.:....|||::.:..|.||..|.:|..|.
pombe   246 AVLTRESSKYEKGKVIKDLSYLNRDLSRVIMIDTNPESWSKQPDNAIAMAPWTGNPKDKELVGLI 310

  Fly   273 AFLQLIAEHQVNDVREVLRYYRQFEDPMEQFKDNQRRLQEQSQESIQNLPTSERQWNLTLLGRSL 337
            ..|:.||...:.|||.||:.|:....|:|.    .||.::...:.|::       ||    .:..
pombe   311 PLLEFIAIMDIKDVRPVLKSYQGKNIPLEY----ARREEKLRTKLIED-------WN----EKKK 360

  Fly   338 RGSS 341
            :|||
pombe   361 KGSS 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttm3	NP_610130.1	CPDc	138..265	CDD:214729	58/127 (46%)
ttm3	NP_610130.1	HIP1_clath_bdg	276..332	CDD:293123	15/55 (27%)
tim50	NP_595583.2	NIF	177..325	CDD:281081	64/147 (44%)
tim50	NP_595583.2	FCP1	<238..452	CDD:227517	49/142 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1326
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H130620
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003614
OrthoInspector	1	1.000	-	-		otm47159
orthoMCL	1	0.900	-	-		OOG6_102279
Panther	1	1.100	-	-	O	PTHR12210
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2489
TreeFam	1	0.960	-	-
	11	10.770