DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2528 and AT1G76140

DIOPT Version :9

Sequence 1:	NP_610129.3	Gene:	CG2528 / 35435	FlyBaseID:	FBgn0032969	Length:	731	Species:	Drosophila melanogaster
Sequence 2:	NP_177741.3	Gene:	AT1G76140 / 843946	AraportID:	AT1G76140	Length:	795	Species:	Arabidopsis thaliana

Alignment Length:	723	Identity:	337/723 - (46%)
Similarity:	452/723 - (62%)	Gaps:	27/723 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RIVYPEARKDGRFEEMIHGYKIKDVYRWLEDPDSVDTQQFVNAQNNISQSFLERSAERENINSKL 88
            ::.||..|:|....:..||.||.|.||||||||:.:.::||.:|..::.|.||:...:|.:...:
plant    74 QLQYPATRRDDSVVDDYHGVKIGDPYRWLEDPDAEEVKEFVQSQVKLTDSVLEKCETKEKLRQNI 138

  Fly    89 TKLWNFPKYGCPMRHGNYYYFFKNTGLQNQSVLMQQKTLESPESIFLDTNSISSDGTTAISHIKF 153
            |||.:.|:|..|.|.|:.|::|.|||||.||||..|..|::...:.||.|::|.|||.|::....
plant   139 TKLIDHPRYDSPFRQGDKYFYFHNTGLQAQSVLYMQDNLDAEPEVLLDPNTLSDDGTVALNTFSV 203

  Fly   154 SEDGAFMAYGLSESGSDWNKIRIRNTKEGIDLPEILEKVKFSNVSWTKDSKGFFYGRY---TDQD 215
            |||..::|||||.|||||..|::...::....|:.|..|||:.::||.||||||||||   .:.:
plant   204 SEDAKYLAYGLSSSGSDWVTIKLMKIEDKKVEPDTLSWVKFTGITWTHDSKGFFYGRYPAPKEGE 268

  Fly   216 GIFDGSETKLAENQKLYYHLLGESPHQDILIAEFPEHPSWRFKTDISDCGKYLILSISHTVRD-N 279
            .|..|:||......:||||.:|....||||.....|:|.:.|..:::|.|||||:||..:... |
plant   269 DIDAGTETNSNLYHELYYHFIGTDQSQDILCWRDNENPKYMFGAEVTDDGKYLIMSIGESCDPVN 333

  Fly   280 MLYYAELGS--------EEKNAFQLELKPIVDKFEADFDYITNEGSNLYFHTNKDAPNYRVIVID 336
            .|||.::.|        ...::| |....:||.|:|.:..|:|:.:...|.||||||.|:::.:|
plant   334 KLYYCDMTSLSGGLESFRGSSSF-LPFIKLVDTFDAQYSVISNDETLFTFLTNKDAPKYKLVRVD 397

  Fly   337 VNNPAEEHWTTPIPEHKKDVLEWAKCVDGNKLVVCYNCDVKHILQARDLSTGKLIRQFGLDIGSI 401
            :..|  ..||..:.||:||||..|..|:||.||.||..|||||||.|||.:|.|:.|..|||||:
plant   398 LKEP--NSWTDVVEEHEKDVLASACAVNGNHLVACYMSDVKHILQIRDLKSGSLLHQLPLDIGSV 460

  Fly   402 NGISGKKSNSEIFYGFSSFLSPGIIFYYDFAKPSEKPTVLREISLNLEGFSRDNYSVEQVFYKST 466
            :.:|.::.::..|:.|:|||:||:|:..|.|..|.:..|.||::  :.||.|:.:...||||.|.
plant   461 SDVSARRKDNTFFFSFTSFLTPGVIYKCDLANESPEVKVFREVT--VPGFDREAFQAIQVFYPSK 523

  Fly   467 DDTDIPMFIVQRKRDIA--EPRPCLLYGYGGFNYSLMPSFGILSLMFMDTFDGVLAFPNLRGGGE 529
            |.|.|||||| .|:||.  ...|||||.|||||.|:.|||....::.......|..|.|:|||||
plant   524 DGTKIPMFIV-AKKDIKLDGSHPCLLYAYGGFNISITPSFSASRIVLSKHLGVVFCFANIRGGGE 587

  Fly   530 YGMEWHNGGRMLSKQNVFNDFQAAAEFLTKNNYTTKDRLAIQGASNGGLLVGACINQRPDLFGAA 594
            ||.|||..|.:..|||.|:||.:.||:|....||...:|.|:|.|||||||||||||||||:|.|
plant   588 YGEEWHKAGSLAKKQNCFDDFISGAEYLVSAGYTQPSKLCIEGGSNGGLLVGACINQRPDLYGCA 652

  Fly   595 VAQVGVMDMLRFHKFTIGHAWCSDYGNPDEKVHFANLIKFSPLHNVHIPLNPNQ----EYPSTLI 655
            :|.||||||||||||||||||.||||..:.:..|..|||:||||||..|.....    :||||::
plant   653 LAHVGVMDMLRFHKFTIGHAWTSDYGCSENEEEFHWLIKYSPLHNVKRPWEQQTDHLVQYPSTML 717

  Fly   656 LTADHDDRVSPLHSYKFVAALQEAVRYS---EYQLNPILLRVYTKAGHGAGKPTKMRISEATDII 717
            |||||||||.||||.|.:|.||..:..|   ..|:|||:.|:..|||||||:||:..|.||.|..
plant   718 LTADHDDRVVPLHSLKLLATLQHVLCTSLDNSPQMNPIIGRIEVKAGHGAGRPTQKMIDEAADRY 782

  Fly   718 TFFKKTLN 725
            :|..|.:|
plant   783 SFMAKMVN 790

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2528	NP_610129.3	Peptidase_S9_N	28..442	CDD:280970	177/425 (42%)
CG2528	NP_610129.3	Peptidase_S9	516..727	CDD:278741	124/217 (57%)
AT1G76140	NP_177741.3	Peptidase_S9_N	78..501	CDD:280970	177/425 (42%)
AT1G76140	NP_177741.3	Peptidase_S9	560..792	CDD:278741	127/231 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	345	1.000	Domainoid score	I231
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2042
Inparanoid	1	1.050	678	1.000	Inparanoid score	I146
OMA	1	1.010	-	-		QHG63012
OrthoDB	1	1.010	-	-		D225446at2759
OrthoFinder	1	1.000	-	-		FOG0005219
OrthoInspector	1	1.000	-	-		mtm1131
orthoMCL	1	0.900	-	-		OOG6_101804
Panther	1	1.100	-	-	O	PTHR42881
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3731
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.980