Protein Alignment CG2528 and Prep

DIOPT Version :10

• Sequence 1: NP_610129.3
• Gene: CG2528 / 35435
• FlyBaseID: FBgn0032969
• Length: 731
• Species: Drosophila melanogaster
• Sequence 2: NP_035286.1
• Gene: Prep / 19072
• MGIID: 1270863
• Length: 710
• Species: Mus musculus
• Alignment Length: 711
• Identity: 365/711 - (51%)
• Similarity: 472/711 - (66%)
• Gaps: 7/711 - (0%)

  Fly    23 LRIVYPEARKDGRFEEMIHGYKIKDVYRWLEDPDSVDTQQFVNAQNNISQSFLERSAERENINSK 87
            |...||:..:|....:..||:||.|.|.|||||||..|:.||.|||.|:..|||:...|.....:
Mouse     2 LSFQYPDVYRDETSVQEYHGHKICDPYSWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKER 66

  Fly    88 LTKLWNFPKYGCPMRHGNYYYFFKNTGLQNQSVLMQQKTLESPESIFLDTNSISSDGTTAISHIK 152
            :|:|:::|||.|..:.|..|::|.|||||||.||..|.:||....:|||.|::|.|||.|:....
Mouse    67 MTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNTLSDDGTVALRGYA 131

  Fly   153 FSEDGAFMAYGLSESGSDWNKIRIRNTKEGIDLPEILEKVKFSNVSWTKDSKGFFYGRYTDQDGI 217
            |||||.:.|||||.|||||..|:........:||::||:|||:.::||.|.||.||..|..|||.
Mouse   132 FSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQQDGK 196

  Fly   218 FDGSETKLAENQKLYYHLLGESPHQDILIAEFPEHPSWRFKTDISDCGKYLILSISHTVRD-NML 281
            .||:||....:|||.||:||....:|||.||||:.|.|....::||.|:|::|||...... |.|
Mouse   197 SDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIWEGCDPVNRL 261

  Fly   282 YYAELGSEEKNAFQLELK--PIVDKFEADFDYITNEGSNLYFHTNKDAPNYRVIVIDVNNPAEEH 344
            :|.:| .:|.|.....||  .::|.||.::||:||||:...|.||:::||||:|.||..:|.|..
Mouse   262 WYCDL-QQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRNSPNYRLINIDFTDPDESK 325

  Fly   345 WTTPIPEHKKDVLEWAKCVDGNKLVVCYNCDVKHILQARDLSTGKLIRQFGLDIGSINGISGKKS 409
            |...:|||:||||||..||..|.||:||..|||:|||..||:||.|::.|.||:||:.|.||:|.
Mouse   326 WKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSVVGYSGRKK 390

  Fly   410 NSEIFYGFSSFLSPGIIFYYDFAKPSEKPTVLREISLNLEGFSRDNYSVEQVFYKSTDDTDIPMF 474
            :|||||.|:||||||:|::.|..|...:|.|.||::  ::|....:|...|:||.|.|.|.||||
Mouse   391 DSEIFYQFTSFLSPGVIYHCDLTKEELEPMVFREVT--VKGIDAADYQTIQIFYPSKDGTKIPMF 453

  Fly   475 IVQRKR-DIAEPRPCLLYGYGGFNYSLMPSFGILSLMFMDTFDGVLAFPNLRGGGEYGMEWHNGG 538
            ||.:|. .:....|..||||||||.|:.|::.:..|:|:....||||..|:|||||||..||.||
Mouse   454 IVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGG 518

  Fly   539 RMLSKQNVFNDFQAAAEFLTKNNYTTKDRLAIQGASNGGLLVGACINQRPDLFGAAVAQVGVMDM 603
            .:.:|||.|:|||.|||:|.|..||:..||.|.|.|||||||.||.||||||||..:||||||||
Mouse   519 ILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDM 583

  Fly   604 LRFHKFTIGHAWCSDYGNPDEKVHFANLIKFSPLHNVHIPLNPNQEYPSTLILTADHDDRVSPLH 668
            |:||||||||||.:|||..|.|.||..|:|:||||||.:|...:.:|||.|:|||||||||.|||
Mouse   584 LKFHKFTIGHAWTTDYGCSDTKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLH 648

  Fly   669 SYKFVAALQEAVRYSEYQLNPILLRVYTKAGHGAGKPTKMRISEATDIITFFKKTLNVDCI 729
            |.||:|.||..|..|..|.||:|:.|.|||||||||||...|.|.:|:..|..:.||::.|
Mouse   649 SLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIEWI 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2528	NP_610129.3	PreP	22..724	CDD:441114	362/704 (51%)
Prep	NP_035286.1	PreP	4..704	CDD:441114	361/702 (51%)