DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1428 and CG10730

DIOPT Version :9

Sequence 1:	NP_610127.1	Gene:	CG1428 / 35433	FlyBaseID:	FBgn0032967	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_610021.3	Gene:	CG10730 / 35291	FlyBaseID:	FBgn0032843	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	511	Identity:	137/511 - (26%)
Similarity:	223/511 - (43%)	Gaps:	62/511 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 IRCSDKFKASKYHDVLYFLSPPDPK-----LMSTESS-EKLSVMVLGIDSVSHMHFVRYFPLVMA 204
            :|...|.:.....|.:.|:....||     .:..||. .|.||:::|:||.|.::..|..|.|..
  Fly   148 VRDVTKHRELLQQDAISFIEDRLPKEKVKDFVKDESEVHKPSVLIMGLDSTSRINLRRAMPSVYK 212

  Fly   205 FLENHPHTKFFGYSRVGLDANANLVPFLGGKSSRAAGS--DILS----DEKAWLWDSFKMEGYST 263
            |:......:..||::||.:...||:..|.|.|.:..|.  |:..    |...::|..||...|:|
  Fly   213 FVRQPGWFEMQGYNKVGDNTFPNLLAALTGDSEKGVGDYCDVTKPGCLDSLNFIWKRFKKANYTT 277

  Fly   264 AYGEDNAKGILSNRNGDKE-LPKSPVDFDLTPVIVEMNNHTRYSIDLKEMIHCTAGRKFQDVLRD 327
            |:.||.:.  :|..|..|. ..|.|.|:.|.|::..:....:.:.|. ...:|.........:.|
  Fly   278 AFAEDCSS--ISTFNYLKPGFVKQPTDYYLRPLLFAIEKQFKVTNDF-GFAYCVGRHLSFSYVWD 339

  Fly   328 FVLQLVPYMQG-MPFFSFFWQSQGVQEYYEYAWHLDLSYMMLLKKLLDADILNNTLLFLMSDHGL 391
            |..|.:....| .|.|.|.|.:....:|||.|..||......||...::::...:::.||||||.
  Fly   340 FGQQFIDRFLGRSPMFGFLWSNSFTHDYYEGATALDNLLWKYLKSFEESNLFQKSIVILMSDHGH 404

  Fly   392 RAGEYRMSLQGMKEESQPLMVAIYPEWLKRKYPLAVGNLESNAHSLITPYDLRETLADVIALGQL 456
            |....|.:..|..||..|:|....|.|.:||||....||..|.:.|.:.||:..||..:
  Fly   405 RYNTLRRASTGYFEERMPMMFIYLPPWFRRKYPHLASNLGKNQNRLSSNYDVYMTLQHL------ 463

  Fly   457 KDANIEVSMKRLQSHPPNRLPRGI----SLFLPIPDHRTCDLAHIPSLFCFCRELTEVPTDDGLV 517
                :::..|.:...|.|...|..    |||..:|.:|||.:|.|...:|.|:. ||..|:...|
  Fly   464 ----LQLDSKSVDEFPDNLRARQCKSCQSLFFELPFNRTCQMAGIEEKWCCCQP-TETITNSPHV 523

  Fly   518 LRSSRFMVESINQLIKPFG---QCRQLKLEMV-------LLAHFL---DFGEESFVYELRLRVRT 569
            ...:..:|:.:|:.:....   .|....|:.|       :|::.|   |..|:.::    :...|
  Fly   524 STIAEAIVQRMNEHLISHNLSDLCHNFTLDYVEKADRKTILSNGLRPADKNEQVYI----IVFET 584

  Fly   570 SPGNGVYEATVRLS---------DVLLLTSPISRVSHYLGQSHCIGDPDLQIFCLC 616
            .|.|.::|||||.:         ||    ..:||::.|...::||...:.:.:|:|
  Fly   585 VPKNPIFEATVRWNSRTQRLLHFDV----EELSRLTSYKNDANCINRKNAKKYCIC 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1428	NP_610127.1	DUF229	68..547	CDD:281053	116/428 (27%)
CG1428	NP_610127.1	ALP_like	180..453	CDD:293745	83/280 (30%)
CG10730	NP_610021.3	DUF229	55..556	CDD:281053	115/421 (27%)
CG10730	NP_610021.3	ALP_like	188..467	CDD:293745	83/291 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950