Protein Alignment tsh and tshz2

DIOPT Version :9

• Sequence 1: NP_523615.2
• Gene: tsh / 35430
• FlyBaseID: FBgn0003866
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: XP_002935441.3
• Gene: tshz2 / 100497744
• XenbaseID: XB-GENE-486894
• Length: 1024
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 160/779 - (20%)
• Similarity: 251/779 - (32%)
• Gaps: 298/779 - (38%)

  Fly   177 EEEEFDDGANNPLDLSVGTRKRGH----ESEPQLGHIQVKKMFKSDSPPANSVASPSASQLLPGV 237
            ::||.||.:|     |:..::...    :.|.::|. ::|:.|...|.|.:.:.:
 Frog    29 DDEEEDDDSN-----SIAQQQDSSYSPTDEEQEIGG-ELKRSFGYQSSPGSHLCN---------- 77

  Fly   238 NPYLAAVAAANIFRAGQFPDWNSKNDLVVDPLEKMSDIVKGGASGMGTKEKMHSSKATTPQAASQ 302
                              .|..|:: :|.|..:|.|||     .|..:|:             :|
 Frog    78 ------------------QDGESES-VVSDSSDKGSDI-----KGPSSKD-------------AQ 105

  Fly   303 PPKSPVQPTPNQNSESGGGSGGGAAGSGAVTK---ARHNIW-QSHWQNKGVASSVFRCVWCKQSF 363
            .||:...|.|.            |.|...:.|   |..||. .|:|:..|:
 Frog   106 DPKTSPAPKPQ------------AEGHDCMNKMKTAYANILSDSYWERIGL-------------- 144

  Fly   364 PTLEALTTHMKDSKHCGVNVPPFGNLPSNNPQPQHHHPTPPPPPQNHNLRK--HSSGSASNHSPS 426
                            .|.||                         |:.||  .|...||
 Frog   145 ----------------NVKVP-------------------------HSERKVCESRNGAS----- 163

  Fly   427 ANVKNAFQYRGDPPTP-----LPRKLVRGQNVWLGKGVEQAMQI-----------------LKCM 469
               |..|.:..|..:.     ||.|.|...|::      .::|:                 .:|.
 Frog   164 ---KTDFDWHQDALSKSLQQNLPSKSVSKPNLF------SSVQLYRQNAKMYGTVFTGASRFRCR 219

  Fly   470 RCGESFRSLGEMTKHMQETQHYTNILSQEQSISIKSGNANANSDAKESHNSLSSEESRTLSAVLT 534
            :|..::.:|.|:|.||.||.||       |..:.|.....:.|.:|....:....:......||.
 Frog   220 QCSAAYDTLVELTVHMNETGHY-------QDDNRKKDKCISTSYSKSRKRAFHDMDKEDAQKVLK 277

  Fly   535 CKVCDKAFNSLGDLSNHMAKNNHYAE-PLLQSAGARKRPAPKKREKSL-PVRKLL---------- 587
            |..|..:|:||.|||.||.|..||.: ||       |.|.|....|.: |.||.:
 Frog   278 CMFCGDSFDSLQDLSVHMIKTKHYQKVPL-------KEPIPTLSSKLVSPARKRVFEATRPCSPD 335

  Fly   588 EMKGGSGTTQEDHSNEKTSVQGKPGLGPGGGDKNDAALFAERMRQYITGVKAPEEIAKVAAAQLL 652
            ...|..|.....|.|....:......|...|        |....|:        |..|....:.:
 Frog   336 STTGSFGDHGSSHKNGSVQLSSNNRYGYQNG--------ASYTWQF--------EACKSQILKCM 384

  Fly   653 AKNKSPELVEQ------------KNGGSAKAAGASSVLS--AIEQMFTTSFDTPPRHASLPASSP 703
            ....|.:.::|            |...||...|...||.  |:|:|           .||..|||
 Frog   385 ECGSSHDTLQQLTTHMMVTGHFLKVTNSASKKGKQLVLDPLAVEKM-----------QSLSESSP 438

  Fly   704 SNSSTKNTSPVASSILKRLGIDETVDYNKPLIDTNDPYYQHYRYTSSERSGSECSAEARPRLDAP 768
                  |.||                 :||.  ||.|            |||     :.|.|.|.
 Frog   439 ------NDSP-----------------SKPF--TNSP------------SGS-----STPELKAC 461

  Fly   769 TPEKQQQ-GGGHDEESSKPAIKQEREAESKPVKMEIKSEFVDEPNEAEETSKMEAAVVNGSATNN 832
            ...:... ..|:.||.|:.: ::..:|..||:...:|.:::.| .:.::.|| |...:..|..|.
 Frog   462 KESRSDNLEDGNKEEKSETS-EEPEDAVEKPLDPTLKYQYLRE-EDLDDGSK-EGGDILKSLENT 523

  Fly   833 NNNIVERSSPKTPSSAASPQ------------------TRLLPPRSPAESQ-RSVTPKSPASSH 877
            ..:.:.::...|||.:|.|.                  |:::..|:...:: |.:.|||.:.||
 Frog   524 VTSAINKAQNGTPSWSAYPSIHAAYQITDVIKPSVSLGTQVMQMRNTFSNKFRPIAPKSKSVSH 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tsh	NP_523615.2	zf-C2H2_2	<354..>382	CDD:289522	0/27 (0%)
		C2H2 Zn finger	356..378	CDD:275371	0/21 (0%)
		C2H2 Zn finger	468..490	CDD:275371	9/21 (43%)
		C2H2 Zn finger	535..557	CDD:275371	11/21 (52%)
tshz2	XP_002935441.3	homeodomain	833..901	CDD:238039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9401
Panther	1	1.100	-	-	O	PTHR12487
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4785
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.130