Protein Alignment CG11630 and R03G8.3

DIOPT Version :9

• Sequence 1: NP_610124.1
• Gene: CG11630 / 35429
• FlyBaseID: FBgn0032964
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_510174.3
• Gene: R03G8.3 / 181437
• WormBaseID: WBGene00010998
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 640
• Identity: 144/640 - (22%)
• Similarity: 243/640 - (37%)
• Gaps: 170/640 - (26%)

  Fly    76 NLNLTSFSNCTYNYLRTEVNMELAKARFGVETLES-----FKCMYYAMERHTDFDNRYLYSREFE 135
            |:.:...|||  |..|..:.. |....:||...::     .:|       ||....||
 Worm    88 NMEVNPISNC--NKSREPLTF-LNNGSWGVVNKKTKLICRARC-------HTRKSERY------- 135

  Fly   136 LLTDGNNTIEP---HADIIRAECFINATSIYNGVHFYVHPTDEWLRTAQGLPPLKLASDVGSLSV 197
             ...||.|..|   :.:::.|.|......:|..:|..|      :.|....|.:|: |::.:..|
 Worm   136 -NVIGNWTYTPGPINCEVVEAVCADGKKDVYGFLHTQV------IATPPKQPTVKV-SELKNYDV 192

  Fly   198 LIVGLDSISQMHFHRSMARTANFLLSLPHVELKGF---NRLGEDGFDSLMPLLSGL-SGQELKDV 258
            .::.|||:|.....||:.||.:::.:  |::...|   |::|    |:..|..:.| .|:.|:.:
 Worm   193 TVIMLDSLSFTQAKRSLLRTISYMTN--HMDAVLFPYINKVG----DNSRPNGAALWFGKSLEKL 251

  Fly   259 SSNLSSLDSCPFIW-----------------KVFQKAGYETGLGEDNIDKSL---FVKGFRKPPT 303
            ..:|...::.|..|                 |.:|..||:|.:.||..:.:|   ..|||.|||.
 Worm   252 DRSLFEEENVPVDWSHAYMCHVYKDNETSLFKEYQNYGYKTLMAEDWAEGTLNWPNCKGFDKPPI 316

  Fly   304 DFYLRP------------ALLEMWLKTRTDGLFGTHCNEKDNYAMVLREFLFKMLPHHTSHRFFT 356
            |..:||            .|.:..||.:      .:|.| |::.::  ::|.:.:..:.....|.
 Worm   317 DHLMRPFQNALERANHGEPLTKSHLKNQ------KYCRE-DHHTLL--DYLSQFINAYPDQNKFR 372

  Fly   357 FLWWT-------QGIDHLFNYGRKLDQPFLKMFKAIGRSGLLKNTVLLVVSNHGLNKGRFYKTVQ 414
            ::|.:       .|..|       .|:.|.|..  |.....|.|:.:..:.:|||..|...||..
 Worm   373 WIWASILGHDSENGFPH-------SDKDFHKFL--IKHREQLDNSFVFFMGDHGLRFGNVRKTFV 428

  Fly   415 GKVEESQPLAILCYPRWLEERYPQAIGNL---KSNNRRLVTAFDLHATL------QNLPNLTSLE 470
            |.::.|.|...:..|:.|.    |..|.|   :.|.:::.|.||..||:      |:..|.|.|:
 Worm   429 GTLDVSNPFLAVSIPKNLR----QTTGLLNVMRENAQKIQTHFDTRATMLDILKYQSASNFTDLD 489

  Fly   471 DEQLQQRRVDLWAMGKDIPRGISLFLPIPD-HRDCFLAAIPTANCLCQ-QPRNVSTSDGYVQRAA 533
                     .|...|:   :|.|.....|| .|:|....||...|:|| ....|||.....:...
 Worm   490 ---------PLIIPGE---KGYSYIRTQPDILRNCRNMPIPMQYCICQFNKTQVSTKSETAKGVG 542

  Fly   534 RLIIRNLNKMIH--THTPPCKTLYLDRVLTADKWRRIADEHQSEFRVRLIATPGEGQFEGIVRYT 596
            ..:...:|..|.  ..|..|..:.:|.|::..::                    :.:|:|.:.||
 Worm   543 EAVALAVNNEIEEGKFTDKCVKMKVDHVVSLLQF--------------------DQKFKGSMLYT 587

  Fly   597 G-----------YK----------LAVDGHISRVNDYRNGSQCIRNYLIEMYCFC 630
            .           ||          :.|.|.:.|.|.|.:.:.||.:.....||:|
 Worm   588 AVVEMTKPSKAVYKANVKILENGEVKVLGMVERSNKYGSTAYCIGSEHHRPYCYC 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11630	NP_610124.1	DUF229	66..560	CDD:281053	127/547 (23%)
		ALP_like	195..467	CDD:293745	77/323 (24%)
R03G8.3	NP_510174.3	DUF229	92..570	CDD:281053	126/542 (23%)
		ALP_like	190..480	CDD:293745	75/317 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D306348at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.980