DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31612 and znf711

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_001352539.1	Gene:	znf711 / 562505	ZFINID:	ZDB-GENE-081107-49	Length:	765	Species:	Danio rerio

Alignment Length:	552	Identity:	132/552 - (23%)
Similarity:	207/552 - (37%)	Gaps:	158/552 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   462 LHLLDSSHKEVLLALNRSVPICIAQRRRIQCSRC--GMEFLYNIQLRQHSITEHPGLALTGTAAD 524
            |.:.||      ::.:|::...|.:|||.:..:|  ||.|...|......:|.:|
Zfish   340 LQITDS------ISTSRALKQKIKKRRRGETRQCQTGMSFSVIIGPDGQPLTVYP---------- 388

  Fly   525 EYQSRFRCNLCGSSQKSRLALQRH-KKHKHHL--ARYFCAIC------RLEFDNSLDARRHRSLV 580
                   |::||...|||..|:|| |.|..|:  .:|.|..|      ::.|.|.|::.:   |:
Zfish   389 -------CHICGKKFKSRGFLKRHMKNHPDHMFKKKYQCTDCEFTTNKKVSFHNHLESHK---LI 443

  Fly   581 IHKQKARPQTSIPQPENEIEHMLREVLEETVPSPPAKRSADVNAKCSNSRKTIESSQRLAQHQAE 645
            |..:|      ||           |..|.|
Zfish   444 IKNEK------IP-----------EYTEYT----------------------------------- 456

  Fly   646 VHSSDNHLCLSCGISFESAQALGRHTRSCQPLASTSTPADLSQAQKKSMYSCDQCRFQSQYESDL 710
                                   |......||:|...   :.:.::..::.|..|.:::. |..|
Zfish   457 -----------------------RRYHEASPLSSNKL---ILRDKEPKLHKCKYCEYETA-EQGL 494

  Fly   711 VYHRIFHTRSGTIGKNEVLQCPLCPKNFKKHS-LRAHLRNHTNEKIFECTECLQKFARRHNLKNH 774
            :...:....|    ||....|..|.|.|:..| |:.|:|.||.||.|.|..|....|.:.|||.|
Zfish   495 LNRHLLAVHS----KNFAHVCVECAKGFRHPSELKKHMRTHTGEKPFHCQHCEFSCADQSNLKTH 555

  Fly   775 VITKHA-----KVG--------DKEKKKYAAKDVEQSKPKYQCGTCGKLLAKKYSLKLHEIS-HS 825
            :.:||.     |.|        |||.:::|  ::.|....:||..|.........||.|.|| |:
Zfish   556 IKSKHGTDLPFKCGHCPQAFADDKELQRHA--EIFQGHKTHQCPHCEHKSTNSSDLKRHIISVHT 618

  Fly   826 KAVERNYLCHFAD-CSYAGRTPESLKTHLVSH-SQENHKCARINCSYVGKSELHLKRHLKSAHST 888
            |...     |..| |......|..||.|..:| ..:.|:|.  :|.:.......|.||:.|.|:.
Zfish   619 KDFP-----HKCDVCEKGFHRPSELKKHSETHKGNKVHQCR--HCDFKTLDPFTLSRHILSVHTK 676

  Fly   889 EKNGEEWFSCDQCDFRARIKGHLRRHSLRHSGQKPHQCPHCDFQCSTIDNLRKHIIKTGKHPGMF 953
            :..    |.|.:|....|.:..|::|...|||:|.:||.:|::..:.....::|:|..  |...:
Zfish   677 DLP----FKCKRCKRGFRHQNELKKHMKTHSGRKVYQCQYCEYNTTDASGFKRHVISI--HTKDY 735

  Fly   954 IYHCAKCSDEEAGEIFKSNSYKEYQHHLKTHK 985
            .:.|..|.     :.|:..|.|. ||.::.||
Zfish   736 PHRCDYCK-----KGFRRPSEKN-QHIMRHHK 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	4/19 (21%)
		C2H2 Zn finger	731..750	CDD:275368	8/19 (42%)
		C2H2 Zn finger	758..779	CDD:275368	7/20 (35%)
		C2H2 Zn finger	804..824	CDD:275368	7/20 (35%)
		C2H2 Zn finger	834..856	CDD:275368	7/22 (32%)
		C2H2 Zn finger	898..918	CDD:275368	5/19 (26%)
		zf-H2C2_2	910..935	CDD:290200	9/24 (38%)
		C2H2 Zn finger	926..945	CDD:275368	3/18 (17%)
		C2H2 Zn finger	957..984	CDD:275368	7/26 (27%)
znf711	NP_001352539.1	Zfx_Zfy_act	64..368	CDD:309717	8/33 (24%)
		COG5048	385..763	CDD:227381	119/501 (24%)
		C2H2 Zn finger	389..409	CDD:275368	10/19 (53%)
		C2H2 Zn finger	482..503	CDD:275368	4/21 (19%)
		C2H2 Zn finger	511..531	CDD:275368	8/19 (42%)
		C2H2 Zn finger	539..560	CDD:275368	7/20 (35%)
		C2H2 Zn finger	568..584	CDD:275368	4/15 (27%)
		C2H2 Zn finger	596..617	CDD:275368	7/20 (35%)
		C2H2 Zn finger	625..645	CDD:275368	6/19 (32%)
		C2H2 Zn finger	682..702	CDD:275368	5/19 (26%)
		C2H2 Zn finger	710..731	CDD:275368	4/22 (18%)
		C2H2 Zn finger	739..759	CDD:275368	7/25 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100