DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31612 and CG4424

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	83/374 - (22%)
Similarity:	127/374 - (33%)	Gaps:	132/374 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   515 GLALTGTAADEYQSRFRCNLCGSSQKSRLALQRHKKHKHHLARYFCAICRL--EF------DNSL 571
            |:.:..||.:|......|..|    |:.|.|    .||      |..||:.  ||      .:::
  Fly    48 GIQIRATAKEEVLPTRICLRC----KAFLTL----AHK------FRQICQRSNEFLREYVIKDAV 98

  Fly   572 DARRHRSLVIHKQKARPQTSIPQPENEIEHMLREVLEETV----------PSPPAKRSADVNAKC 626
            :....:.:|   |:.||.|..|....::|....|||||.|          |..||::
  Fly    99 EQGVVKEVV---QQTRPSTPPPIETEQLEPPEDEVLEEGVWSTEDPIEETPHGPAEK-------- 152

  Fly   627 SNSRKTIESSQRLAQHQAEVHSSDN-----------HLCLSCGISFESAQALGRHTRSCQPLAST 680
              .|.|:.:.:.|........|:..           |:|..||..:.....|..|.|
  Fly   153 --ERPTVLTVEMLPAPYPPPASTPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMR-------- 207

  Fly   681 STPADLSQAQKKSMYSCDQCRFQSQYESDLVYHRIFHTRSGTIGKNEVLQCPLCPKNFKKHSLRA 745
                   :...:..|.|:.|            |:.||.                     .:.|:.
  Fly   208 -------RHNDERPYECEIC------------HKSFHV---------------------NYQLKR 232

  Fly   746 HLRNHTNEKIFECTECLQKFARRHNLKNHVITKHAKVGDKEKKKYAAKDVEQSKPKYQCGTCGKL 810
            |:|.||..|.:.|..|.:.||.|.:|     .||.:....|:             .|.|.||||.
  Fly   233 HIRQHTGAKPYTCQYCQRNFADRTSL-----VKHERTHRNER-------------PYACKTCGKK 279

  Fly   811 LAKKYSLKLHEISHSKAVERNYLCHFADCSYAGRTPESLKTH-LVSHSQ 858
            ......||:|..:|:.  |:.::|...:.|:|       :.| ||:|.|
  Fly   280 FTYASVLKMHYKTHTG--EKPHICQLCNKSFA-------RIHNLVAHLQ 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	3/19 (16%)
		C2H2 Zn finger	731..750	CDD:275368	3/18 (17%)
		C2H2 Zn finger	758..779	CDD:275368	6/20 (30%)
		C2H2 Zn finger	804..824	CDD:275368	8/19 (42%)
		C2H2 Zn finger	834..856	CDD:275368	6/22 (27%)
		C2H2 Zn finger	898..918	CDD:275368
		zf-H2C2_2	910..935	CDD:290200
		C2H2 Zn finger	926..945	CDD:275368
		C2H2 Zn finger	957..984	CDD:275368
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	16/57 (28%)
		C2H2 Zn finger	189..209	CDD:275368	6/34 (18%)
		DUF45	<204..281	CDD:302795	29/142 (20%)
		COG5048	210..>345	CDD:227381	40/170 (24%)
		C2H2 Zn finger	217..237	CDD:275368	8/52 (15%)
		C2H2 Zn finger	245..265	CDD:275368	8/24 (33%)
		zf-H2C2_2	257..282	CDD:290200	10/42 (24%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	8/32 (25%)
		C2H2 Zn finger	301..320	CDD:275368	8/26 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100