DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31612 and F21A9.2

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_491204.3	Gene:	F21A9.2 / 184756	WormBaseID:	WBGene00017651	Length:	392	Species:	Caenorhabditis elegans

Alignment Length:	325	Identity:	71/325 - (21%)
Similarity:	119/325 - (36%)	Gaps:	77/325 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   634 ESSQRLAQHQAEVHSSDNHLCLSCGIS-FESAQALGRHTRSCQPLASTSTPADLSQAQKK---SM 694
            :.:.||.|.:.|    ..|.|..|.:: |.|...|..|             .||..::||   .:
Worm   111 DMNYRLEQEKLE----KKHECPHCHVAKFNSLHNLKVH-------------EDLYCSKKKLGNVV 158

  Fly   695 YSCDQCRFQSQYESDLVYHRIFHTR------SGTIGKNEVL--QCPLCPKNFKKHSLRAHLRNHT 751
            .:.|..:.|:.....:.:|.:|...      ..|||:|..|  ..||...|.:|    ..:.|.:
Worm   159 ENADSRKQQNVILLPMAFHDLFQQNPFQVVGPVTIGRNSALINSNPLLIHNKRK----LEMPNFS 219

  Fly   752 NEKI---FECTECLQKFARRHNLKNHVITKHA-------KVGDKEKKKYAAKDVEQSKPKYQCGT 806
            ..|:   .......:|..|.....:...:.||       .......|..:::.:...:| :.| |
Worm   220 TSKLSVQIPIINLDEKNVRTSTPLDLSSSPHAPSVPSLSASCSPTSKSSSSEPIYPERP-FSC-T 282

  Fly   807 CGKLLAKKYSLKLHEISHSKAVERNYLCHFADCSYAGRTP---ESLKTHLVSHSQENHKCARINC 868
            ||...:.:.:...|        ::.|..|....|..|..|   :||:       :...||.:  |
Worm   283 CGVSFSSQTTYDAH--------KQLYCSHTTRVSSPGGGPHRNDSLR-------KVPEKCTK--C 330

  Fly   869 SYVGKSELHLKRHLKSAHSTEKNGEEWFSCDQCDFRA----RIKGHLRRHS----LRHSGQKPHQ 925
            .:|..|...|..|::|:|.|.|.    |:|..|.:||    .|:.|:|.||    |:....:|.:
Worm   331 DFVPTSSSQLSMHIRSSHQTTKT----FTCLVCGYRAFSMRGIRTHMRSHSDDEALKFKANEPDE 391

Fly 926 925
Worm 392 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	3/19 (16%)
		C2H2 Zn finger	731..750	CDD:275368	4/18 (22%)
		C2H2 Zn finger	758..779	CDD:275368	2/20 (10%)
		C2H2 Zn finger	804..824	CDD:275368	5/19 (26%)
		C2H2 Zn finger	834..856	CDD:275368	6/24 (25%)
		C2H2 Zn finger	898..918	CDD:275368	10/27 (37%)
		zf-H2C2_2	910..935	CDD:290200	6/20 (30%)
		C2H2 Zn finger	926..945	CDD:275368	71/325 (22%)
		C2H2 Zn finger	957..984	CDD:275368
F21A9.2	NP_491204.3	C2H2 Zn finger	327..348	CDD:275368	7/22 (32%)
F21A9.2	NP_491204.3	C2H2 Zn finger	356..376	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5693
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950