DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31612 and unc-98

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_509284.2	Gene:	unc-98 / 181020	WormBaseID:	WBGene00006827	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	66/327 - (20%)
Similarity:	108/327 - (33%)	Gaps:	74/327 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   572 DARRHRSLVIHKQKARPQTSIPQPENEIEHML------------------REVLEETVPSPPA-- 616
            :||:.|........|.....:....||:.|.|                  :|:::...|:..|
Worm     8 EARKERDDFEELMNACDLAKMSVKNNEMVHGLETFGINGESSENGNKEKPKEIMKVVAPTVEAYV 72

  Fly   617 -KRSADVNAKCSNSRKTIESSQRLAQHQAEVHSSDN----HLCLSCGISFESAQALGRHTRSCQP 676
             ..||....|.|.........|.:.|....|...||    :.|..||::|.....|..|.|.
Worm    73 GSSSAQTPTKSSGGALDGSDQQEVRQDGTSVQKDDNGFVFYKCRFCGLTFNFMNTLRAHERI--- 134

  Fly   677 LASTSTPADLSQAQKKSMYSCDQCRFQSQYESDLVYHRIFHTRSGTIGKNEVLQCPLCPKNFKKH 741
                   .|:||.     |.|.:|....::...|.||...|:      :.:..:|. |.:.|..:
Worm   135 -------HDVSQP-----YVCGKCGDSFEFACQLEYHAAQHS------EIDGYKCE-CGRTFFSY 180

  Fly   742 SLRAHLRNHTNEKIFECTECLQKFARRHNLKNHVITKHAKVGDKEKKKYAAKDVEQSKPKYQCGT 806
            :...: ..||::.:                  .:|........|..||......||..|:....|
Worm   181 TEMLY-HKHTDDPL------------------ELIGAPETTTIKVSKKRVLPVSEQDLPQPAFVT 226

  Fly   807 CGKLLAKKYSLKLHEISHSKAVERNYLCHFADCSYAGRTPESLKTHLVSHSQENHKCARINCSYV 871
            .|  ...|:.|:::....||.    |:|.:...||:  ....|..|:.||..|.:...|.:...:
Worm   227 EG--YEPKHPLRVYNDVRSKP----YICEYCSKSYS--DSRGLAYHMYSHRGEKYFNPRASRYMM 283

  Fly   872 GK 873
            |:
Worm   284 GR 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	5/19 (26%)
		C2H2 Zn finger	731..750	CDD:275368	3/18 (17%)
		C2H2 Zn finger	758..779	CDD:275368	1/20 (5%)
		C2H2 Zn finger	804..824	CDD:275368	4/19 (21%)
		C2H2 Zn finger	834..856	CDD:275368	5/21 (24%)
		C2H2 Zn finger	898..918	CDD:275368
		zf-H2C2_2	910..935	CDD:290200
		C2H2 Zn finger	926..945	CDD:275368
		C2H2 Zn finger	957..984	CDD:275368
unc-98	NP_509284.2	C2H2 Zn finger	115..135	CDD:275368	7/29 (24%)
		C2H2 Zn finger	143..163	CDD:275368	5/19 (26%)
		SFP1	<169..268	CDD:227516	24/126 (19%)
		C2H2 Zn finger	171..189	CDD:275368	3/19 (16%)
		C2H2 Zn finger	248..268	CDD:275368	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100