DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31612 and Y56A3A.28

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_001366955.1	Gene:	Y56A3A.28 / 176632	WormBaseID:	WBGene00013240	Length:	386	Species:	Caenorhabditis elegans

Alignment Length:	325	Identity:	78/325 - (24%)
Similarity:	124/325 - (38%)	Gaps:	60/325 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   637 QRLAQHQAEVHSSDNHLCLSCGISFESAQALGRHTRSC-------QPLASTSTPADLSQAQKKSM 694
            |:..:.::....|.:.|||.|...|.:.:....||..|       :...|.|..||...|:.:..
Worm     4 QKTEEERSWTSISRHFLCLECRKYFRNKREFYWHTEDCLMEAFEREVALSVSRGADEDIAENEEE 68

  Fly   695 YSCDQCRFQSQYESDLVYHRIFHTRSGTIGKNEV-----LQCPLCPKNFKKHSLRAHLRNHTNEK 754
            :. ||     ..|..|          |.|.|||.     .|.|..||:    |.|...:....||
Worm    69 WD-DQ-----PSEEAL----------GLIAKNEASPSKQQQPPPPPKS----SPRKPEKAQKEEK 113

  Fly   755 IFECTECLQKFARRHNLKNHVITKHAKVGDKEKKKYAAKDVEQSKPKYQCGTCGKLLAKKYSLKL 819
            :.......|           :|   ..|..:.:..:.:.|.:.|:|..   ...::..:|..:..
Worm   114 VIAGPRGSQ-----------II---VSVEPQVEAGFQSDDDDDSEPPL---LVSQVEQEKEDINE 161

  Fly   820 HEISHSKAVERNYLCHFADCSYAG-RTPES-LKTHLV---SHSQENHKCARINCSYVGKSELHLK 879
            .:|.::...|...   ..|..|.. .||.| :.:..|   ..:|::....::.|...|   |.|.
Worm   162 EDIGNNDDEEEEM---EGDLEYGDEETPLSFIPSGTVVGAPANQDDGSKPKMECPTCG---LVLY 220

  Fly   880 RHLKSAHSTEKNGEEWFSCDQCDFRARIKGHLRRHSLRHSGQKPHQCPHCDFQCSTIDNLRKHII 944
            ||..:||.....||:.:.||.|..|.|....|:.|...|:|:||:.||.||::..|..||.:||:
Worm   221 RHNFAAHFRIHTGEQPYGCDYCGKRFRTTSSLKVHKRAHTGEKPYVCPSCDYRTITKRNLDRHIV 285

Fly 945 944
Worm 286 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	4/19 (21%)
		C2H2 Zn finger	731..750	CDD:275368	5/18 (28%)
		C2H2 Zn finger	758..779	CDD:275368	2/20 (10%)
		C2H2 Zn finger	804..824	CDD:275368	2/19 (11%)
		C2H2 Zn finger	834..856	CDD:275368	6/26 (23%)
		C2H2 Zn finger	898..918	CDD:275368	7/19 (37%)
		zf-H2C2_2	910..935	CDD:290200	10/24 (42%)
		C2H2 Zn finger	926..945	CDD:275368	9/19 (47%)
		C2H2 Zn finger	957..984	CDD:275368
Y56A3A.28	NP_001366955.1	C2H2 Zn finger	212..231	CDD:275368	8/21 (38%)
		zf-H2C2_2	223..248	CDD:404364	8/24 (33%)
		C2H2 Zn finger	239..259	CDD:275368	7/19 (37%)
		zf-H2C2_2	251..276	CDD:404364	10/24 (42%)
		C2H2 Zn finger	267..287	CDD:275368	9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5693
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950