DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31612 and klu-1

DIOPT Version :9

Sequence 1:	NP_001163042.1	Gene:	CG31612 / 35427	FlyBaseID:	FBgn0051612	Length:	987	Species:	Drosophila melanogaster
Sequence 2:	NP_493611.2	Gene:	klu-1 / 173366	WormBaseID:	WBGene00013970	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	78/376 - (20%)
Similarity:	131/376 - (34%)	Gaps:	118/376 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   621 DVNAKCSNSRKTIESSQRLAQHQAEVHSSDNHLCLSCGISFE--SAQALGRHTRSCQPLASTSTP 683
            |.:..||.:..::.:            :|.||      .|||  |..:||..|.....|.:....
Worm   134 DCDTNCSGTPYSLST------------NSGNH------FSFEARSVSSLGHSTAHFNQLLAAGAA 180

  Fly   684 ADLSQAQKKSMYSCDQCRFQSQYESDLVYHRIFHTRSGTIGKNEVLQCPLCPKNFKKHSLRAHLR 748
            .:||:.:.:|     :...|...|.|     :.|..:.||......:.||       |.....::
Worm   181 YELSRERSRS-----ESDMQPTQEDD-----VRHLNTSTISVPIYAKKPL-------HKFGGEIK 228

  Fly   749 NHTN--------------------------EKIFECTECL-------QKFARRHNLKNHVITKHA 780
            ..::                          :|..|.|...       |.||.::....:::|..:
Worm   229 RSSSTPPPTSDEREQVEQRLLLRPSSGMEIKKDLETTNSFVSSWAREQIFAMQNATMYNLLTARS 293

  Fly   781 -------------KV--GDKEKKKYAAKDVEQSKPK---YQCGTCGKLLAKKYSLKLHEISHSKA 827
                         ||  ..|:...:|.:| :.|:.|   |.|..||:..|....|..|..|.
Worm   294 AEDCSTISTPGPLKVFPRSKDDMTFAPRD-DSSRAKQMQYPCTLCGQAFAVHDRLAKHIASR--- 354

  Fly   828 VERNYLCHFADCSYAGRTPESLKTHLVSHSQENHKCARINCSYVGKSELHLKRHLKSAHSTEKNG 892
             .|...|...|.|                  :.|||...:.|: .:|:: |.||:: .|:    |
Worm   355 -HRQRSCTLDDAS------------------KVHKCNMCSKSF-SRSDM-LTRHMR-LHT----G 393

  Fly   893 EEWFSCDQCDFRARIKGHLRRHSLRHSGQKPHQCPHCDFQCSTIDNLRKHI 943
            .:.:||..|:.......||..|...|:|:||:.||.|::..|..|.:.:|:
Worm   394 AKPYSCPTCNQVFSRSDHLSTHLRTHTGEKPYACPMCNYSASRRDMISRHM 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31612	NP_001163042.1	C2H2 Zn finger	697..717	CDD:275368	3/19 (16%)
		C2H2 Zn finger	731..750	CDD:275368	3/18 (17%)
		C2H2 Zn finger	758..779	CDD:275368	5/27 (19%)
		C2H2 Zn finger	804..824	CDD:275368	6/19 (32%)
		C2H2 Zn finger	834..856	CDD:275368	3/21 (14%)
		C2H2 Zn finger	898..918	CDD:275368	5/19 (26%)
		zf-H2C2_2	910..935	CDD:290200	10/24 (42%)
		C2H2 Zn finger	926..945	CDD:275368	6/18 (33%)
		C2H2 Zn finger	957..984	CDD:275368
klu-1	NP_493611.2	C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)
		zf-C2H2	369..391	CDD:278523	8/24 (33%)
		C2H2 Zn finger	371..391	CDD:275368	6/22 (27%)
		zf-H2C2_2	383..408	CDD:290200	8/30 (27%)
		COG5048	395..>448	CDD:227381	16/50 (32%)
		C2H2 Zn finger	399..419	CDD:275368	5/19 (26%)
		zf-H2C2_2	411..436	CDD:290200	10/24 (42%)
		C2H2 Zn finger	427..447	CDD:275368	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000