DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1416 and HCH1

DIOPT Version :9

Sequence 1:	NP_610121.2	Gene:	CG1416 / 35426	FlyBaseID:	FBgn0032961	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_014118.1	Gene:	HCH1 / 855440	SGDID:	S000005225	Length:	153	Species:	Saccharomyces cerevisiae

Alignment Length:	159	Identity:	47/159 - (29%)
Similarity:	78/159 - (49%)	Gaps:	25/159 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NVNNWHWTEKNATPWSKD----RLHQLFQDFKIGQSDIECAVDSVDKCSGEATVNNRKGKLIFFY 81
            |.|||||.:||..|||||    :|..|......|:|.||  :..|...:|::.|:.||||.|.::
Yeast     5 NPNNWHWVDKNTLPWSKDYLNGKLTSLSTVSSDGKSKIE--LTQVSSITGDSNVSQRKGKPICYF 67

  Fly    82 EWELVLKWSGKLLKNSK-------LIHKGKLTIPNLSEENELADVEITVTIDESNDESETL--KQ 137
            :.:|.:......|..:|       ::..|||.||....:.  :|:.|   :.:..|..:.|  .:
Yeast    68 DLQLSMNVKVTNLDTNKDDEDDDGILADGKLEIPEFMHDE--SDIPI---LSQGFDAFDGLVRSE 127

  Fly   138 FMYNVGRDRVRQQLASYIRELKEEYSKNL 166
            |:     .:|.:.|..|..:|.:|:||::
Yeast   128 FV-----PKVVETLLKYQDDLIKEHSKDI 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1416	NP_610121.2	COG5580	19..347	CDD:227867	47/159 (30%)
		Aha1_N	30..159	CDD:286332	37/141 (26%)
		SRPBCC_Aha1	221..346	CDD:176901
HCH1	NP_014118.1	COG5580	1..>153	CDD:227867	47/159 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13009
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1975
SonicParanoid	1	1.000	-	-		X1482
TreeFam	0	0.000	Not matched by this tool.
	6	5.940