Protein Alignment step and YEL1

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_009493.1
• Gene: YEL1 / 852219
• SGDID: S000000156
• Length: 687
• Species: Saccharomyces cerevisiae
• Alignment Length: 446
• Identity: 89/446 - (19%)
• Similarity: 161/446 - (36%)
• Gaps: 110/446 - (24%)

  Fly   313 SNIHKTNKY-TSKNNNNDSKRESQ-----QSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIK 371
            :.:.|.:.| .|:...||:..||:     ..::..|.:.:|        ||..:|
Yeast     6 NEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNML--------QSPTMV---------- 52

  Fly   372 DELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIE---YLVENRLLRHDPQDVAHF 433
             .:|:::...||.:..:....:........|.:..:....:..:   :|:.:.:|....:||::.
Yeast    53 -NMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDVSYK 116

  Fly   434 LYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMM 498
            .|          .::||  ||.|..||..||.|.......|::.|.....|.....|||.|||::
Yeast   117 EY----------ANFLG--NDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRIL 169

  Fly   499 ETFAQRY--CQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRGINNGGDLP 561
            |..:..:  |..|....:...:|:::.|::::||:.|||....|...:.  .||...|||
Yeast   170 ECLSIEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIK--FSMVAFINN----- 227

  Fly   562 RGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQGGRYKSWKRRWFILNDNCLYYFE 626
              .|.:|.|....|..||                              :.|...|:.:...||
Yeast   228 --TLRALREENEYEELKI------------------------------YSREHLIIEELSEYY-- 258

  Fly   627 YTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVY----- 686
            .|.::.|   :||...|...|:........:.|:|.|:   :...|.:...|.....|:|
Yeast   259 KTLNETP---LPLCTESRTSINISDNQSSLKRFSTLGS---REFSTSNLRSVNSNSTTLYSRDGQ 317

  Fly   687 ----RMSAATEED------------QQEWIKRLTQSISHNPFYDILVQRKKKALSK 726
                .|||.:.::            ::.:...|......:.|.|.|:...||:|.:
Yeast   318 VSVREMSAKSNKNFHNNHPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	45/184 (24%)
		PH_GRP1-like	592..710	CDD:269954	21/138 (15%)
		PH	596..708	CDD:278594	21/132 (16%)
YEL1	NP_009493.1	COG5307	1..687	CDD:227623	89/446 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1799
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000619
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850