DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment step and GNL1

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	NP_001318705.1	Gene:	GNL1 / 833946	AraportID:	AT5G39500	Length:	1443	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	135/499 - (27%)
Similarity:	198/499 - (39%)	Gaps:	138/499 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 DEPNTELI---------SKRTEYKHTTITTTTRTLIVSRP------VEL------LLN--ENGEI 246
            |:|::|::         .|:||..............:..|      ||:      |||  ||||:
plant   273 DDPSSEMVIPETDLRNDEKKTEVSDDLNAAANGENAMMAPYGIPCMVEIFHFLCTLLNVGENGEV 337

  Fly   247 IARRSPRKSRSNSLGRMLDV--------QNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDSS 303
                   .||||.:....||        .:.|..||......|.....:....:.:.|:|    .
plant   338 -------NSRSNPIAFDEDVPLFALGLINSAIELGGPSFREHPKLLTLIQDDLFCNLMQF----G 391

  Fly   304 NSQS------------------ESERNSNIHKTNKYT------SKNNNNDSKRESQQSNLCESCR 344
            .|.|                  .:|....:.....|.      ||:.::..::|.....|.:.||
plant   392 MSMSPLILSTVCSIVLNLYLNLRTELKVQLEAFFSYVLLRIAQSKHGSSYQQQEVAMEALVDLCR 456

  Fly   345 M--------------------------LLDRNY--INTEQS-------DNLVILRRPSKQIKDEL 374
            .                          ||.:|.  :|...|       |.|:      ..::...
plant   457 QHTFIAEVFANFDCDITCSNVFEDVSNLLSKNAFPVNGPLSAMHILALDGLI------SMVQGMA 515

  Fly   375 CEVVSEMEALDVP---------------------------EDCKHSNKDKQMSIGRKKFNMDPKK 412
            ..|..|:.|.|||                           ...||..  |::.:|..:||.||.|
plant   516 ERVGEELPASDVPTHEERYEEFWTVRCENYGDPNFWVPFVRKVKHIK--KKLMLGADRFNRDPNK 578

  Fly   413 GIEYLVENRLL--RHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILV 475
            |::||....||  :.||:.||.|.....||:|..:||:||..:.|...||..|....||.|:.|.
plant   579 GLQYLQGVHLLPEKLDPKSVACFFRYTCGLDKNVMGDFLGNHDQFCIQVLHEFAKTFDFQNMNLA 643

  Fly   476 QALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKD 540
            .|||.|:.:|:|.||||||.|::|.|::||.:.:|.|..:.|..:||:::||:|||..||..||.
plant   644 TALRLFVGTFKLSGEAQKIHRVLEAFSERYYEQSPHILIDKDAAFVLAYSIILLNTDQHNAQVKT 708

  Fly   541 KPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDG 584
            :.|.:.||..||.||.|.||||..|..:|.|||....::.:|.|
plant   709 RMTEEDFIRNNRTINGGADLPREYLSEIYHSIRHSEIQMDEDKG 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	80/181 (44%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
GNL1	NP_001318705.1	PLN03076	<352..>1295	CDD:215560	113/413 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10663
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920