DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment step and AT3G60860

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	NP_191645.1	Gene:	AT3G60860 / 825257	AraportID:	AT3G60860	Length:	1793	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	140/481 - (29%)
Similarity:	209/481 - (43%)	Gaps:	123/481 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 VELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEAD---PCSKNSLPPPP------ 291
            |::.||.:.::        :.||...||::        ||...|.   |.:..:|.||.
plant   489 VDIFLNYDCDV--------NSSNIFERMVN--------GLLKTAQGVPPGTATTLMPPQEAAMKL 537

  Fly   292 -----YIDDMRFIDDSSNSQSESERNSNIHKTN---------KYTSKNNNNDSKRESQQSNLCES 342
                 .:..::.:.|..|.|.....:::::|::         .....|.|.|...:...: ..||
plant   538 EAMKCLVAILKSMGDWLNKQLRLPVSNSLNKSDVIEIDLGPGSPQLANGNADESADGSDT-YSES 601

  Fly   343 CRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFN 407
                      :...||.|.|.:|  :..|.||.|.:|                         .||
plant   602 ----------SGGTSDALAIEQR--RAYKLELQEGIS-------------------------LFN 629

  Fly   408 MDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNL 472
            ..|.||||:|:....:...|:::|.||....|||||.|||||||:.|....|:.|:|...||..:
plant   630 RKPTKGIEFLINAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGM 694

  Fly   473 ILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPS 537
            ...:|:|.||..||||||||||||:||.||:|||:.||.:||:.|:.|||::::|||||..|||.
plant   695 EFDEAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPM 759

  Fly   538 VKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWK 602
            ||:|.:.|.||..||||::|.|||...:.||||.|.....|:.:||..
plant   760 VKNKMSADDFIRNNRGIDDGKDLPADYMRSLYERITKHEIKMKEDDLR----------------- 807

  Fly   603 QGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADII 667
                               |...:|.......|:..:.||.:|:....|       :|....|::
plant   808 -------------------LQQKQYANSNRMLGLDGILNIVIRKQWGDS-------YAETSDDLM 846

  Fly   668 KACKTDSEGKVVEGKHTVYRMSAATE 693
            |..:...:.|..:.:.|.|   |||:
plant   847 KHMQEQFKEKARKSESTYY---AATD 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	88/179 (49%)
		PH_GRP1-like	592..710	CDD:269954	16/102 (16%)
		PH	596..708	CDD:278594	16/98 (16%)
AT3G60860	NP_191645.1	PLN03076	1..1793	CDD:215560	140/481 (29%)
		DCB	6..217	CDD:292830
		Sec7_N	345..499	CDD:289549	3/9 (33%)
		Sec7	617..799	CDD:279680	93/206 (45%)
		DUF1981	1166..1249	CDD:286414
		Mon2_C	1346..>1421	CDD:292823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820