DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment step and ATMIN7

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	NP_189916.4	Gene:	ATMIN7 / 823405	AraportID:	AT3G43300	Length:	1758	Species:	Arabidopsis thaliana

Alignment Length:	705	Identity:	173/705 - (24%)
Similarity:	259/705 - (36%)	Gaps:	211/705 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PGL-GGSESVGRKQPLQRSCLDLSTTRVGCDGCVSLEFFQSESPESRRSNSTFYVNTQNVSSAVF 92
            ||| ||..|......|...|           .||     .:.||:| .......|....|:|..|
plant   143 PGLDGGKNSAPFTDILNMVC-----------SCV-----DNSSPDS-TVLQVLKVLLTAVASGKF 190

  Fly    93 KDNRQPLLERGSGSDSSPSSVCVRCSCNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMA 157
            |.:.:|||        ....||...:.||                ||.|.         ::.|.|
plant   191 KVHGEPLL--------GVIRVCYNIALNS----------------KSPIN---------QATSKA 222

  Fly   158 PYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTT 222
            ..|.:.:....::..|....:|.....:.|:....:.|..|:.....:|....|....|:.|.||
plant   223 MLTQMISIVFRRMETDIVSASSTVSQEEHVSGDTSSPKNEEITAADENEKEMTLGDALTQAKDTT 287

  Fly   223 ITTT--TRTLI-----------VSRPVELLLNENGEIIARRSPRKSRSNSLGR------------ 262
            :.:.  ..||:           :.:.|.|   |:|:.|.|..  :..|.|:|:
plant   288 LASVEELHTLVGGADIKGLEAALDKAVHL---EDGKKIKRGI--ELESMSIGQRDALLVFRTLCK 347

  Fly   263 --MLDVQNEIGT-----------GGLFMEADPCSKNSLPPPPYIDDMR----------------- 297
              |.:..:|:.|           |.|...:...:||.    .:||.::
plant   348 MGMKEDSDEVTTKTRILSLELLQGMLEGVSHSFTKNF----HFIDSVKAYLSYALLRASVSQSSV 408

  Fly   298 -------------------------------FIDDSSNSQSESERNSNIHKTNKYTSKNNNNDSK 331
                                           |.|..|:||.|......|.......:....||.|
plant   409 IFQYASGIFSVLLLRFRDSLKVSMDCYLSPYFSDPKSHSQGEIGIFFPIIVLRSLDNSECPNDQK 473

  Fly   332 RE--SQQSNLCESCRMLLDRNYIN------------------------TEQSDNLVILRRPSKQI 370
            ..  .....:|:..:||:| .|:|                        ::.:|....:...:..:
plant   474 MGVLRMLEKVCKDPQMLVD-VYVNYDCDLEAPNLFERMVTTLSKIAQGSQSADPNPAMASQTASV 537

  Fly   371 KDELCE-VVSEMEAL----------------------------------DVPEDCKHSNKDKQ-M 399
            |....: :|:.:::|                                  |||.:.:.:...|. |
plant   538 KGSSLQCLVNVLKSLVDWEKIRREAENSTRNANEDSASTGEPIETKSREDVPSNFEKAKAHKSTM 602

  Fly   400 SIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFV 464
            .....:||.:..||:|||:.|:|:..:|..||.||.....|:|..||||||:..:|...|:.|:|
plant   603 EAAISEFNRNSVKGVEYLIANKLVERNPASVAQFLRSTSSLSKVMIGDYLGQHEEFPLAVMHAYV 667

  Fly   465 ALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIML 529
            ....|:.:....|:|:||..||||||||||||:||.||:|||..||.:|.|.||.|||::|:|||
plant   668 DSMKFSEMKFHSAIREFLKGFRLPGEAQKIDRIMEKFAERYCADNPGLFKNADTAYVLAYAVIML 732

  Fly   530 NTSLHNPSVKDKPTVDQFISMNRGINNGGD-LPRGLLESLYESIRTEPFKIPQDD 583
            ||..|||.|..|.:...|..|| ..|:..| .|..|||.:|:||..|..|:..||
plant   733 NTDAHNPMVWPKMSKSDFTRMN-ATNDPEDCAPTELLEEIYDSIVQEEIKLKDDD 786

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	85/181 (47%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
ATMIN7	NP_189916.4	PLN03076	24..1758	CDD:215560	173/705 (25%)
		DCB	<102..238	CDD:292830	31/144 (22%)
		Sec7_N	334..501	CDD:289549	26/171 (15%)
		Sec7	599..780	CDD:279680	85/181 (47%)
		DUF1981	1092..1175	CDD:286414
		Mon2_C	1188..>1341	CDD:292823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820