Protein Alignment step and Iqsec1

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_038964676.1
• Gene: Iqsec1 / 686590
• RGDID: 1596313
• Length: 1203
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 174/674 - (25%)
• Similarity: 276/674 - (40%)
• Gaps: 135/674 - (20%)

  Fly     7 KRPSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVG-------CDGCVSLE 64
            :||.:.:..|.||:|.:.:........|||......||...:::...:.|       ....:...
  Rat   169 RRPRLQHSTSVLRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTA 233

  Fly    65 FFQ--------------SESPESRR---SNSTF---YVNTQNVSSAVFKDNRQPLLERGSGSDSS 109
            |.|              ||:..|||   ||...   :...:.|.|:.|:..:..:.     :|.|
  Rat   234 FRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVT-----NDGS 293

  Fly   110 PSSVCVRCSCNSITKSGDRNETPT--MATPKSDIKIALKPPPKPRSPSM-------------APY 159
            .....|...|..::....::..|:  .|...::::.|.....|..:.|:             .|.
  Rat   294 QLGALVPSECGDLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPA 358

  Fly   160 TSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLP-------CDEPNTELISKR-- 215
            :..|....|:..|.........|...|.:.||||..:.|.:..|       .|.|::.....|
  Rat   359 SDTARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLR 423

  Fly   216 -------------TEYKHTTITTTTRTLIVSRPVELLLNENGEIIARRSP---------RKSRSN 258
                         .|.|..|.|:...|..:.||...|..|:..::....|         |..||
  Rat   424 SGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSDRSDRS- 487

  Fly   259 SLGRMLDVQNEIG----------TGGLFMEADPCSKNSLP---------PPPYIDDMRFIDDSSN 304
            ||.|....:..:|          .||        ....||         ||..::....|:.|:|
  Rat   488 SLKRQSAYERSLGGQQGSPKHGPHGG--------PPKGLPREEPELRPRPPRPLESHLAINGSAN 544

  Fly   305 SQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQ 369
            .||:||.:.:....:...|.:|:||:...|.:|:..:|.|          ||:        .|||
  Rat   545 RQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLR----------EQT--------LSKQ 591

  Fly   370 IKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFL 434
            ...:     ....:.|.|.......:.:...||...||..|:|||:||:|...:...|..|||||
  Rat   592 TYHK-----ETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFL 651

  Fly   435 YKGEGLNKTAIGDYLGEK-NDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMM 498
            .:.:||::..||::||.: ..||.|||...|...||:.:.|.:|||:|....|:.|||||::|::
  Rat   652 LQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLI 716

  Fly   499 ETFAQRYCQLNPDI---FTNTDTCYVLSFAIIMLNTSLHNPSVKD--KPTVDQFISMNRGINNGG 558
            |.|:||||..||.:   |.|.||.::|:||||:|||.:::|:||.  |..::.|:...||:::|.
  Rat   717 EAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGE 781

  Fly   559 DLPRGLLESLYESIRTEPFKIPQD 582
            |:||..|..:||.||....|..:|
  Rat   782 DIPRETLIGIYERIRKRELKTNED 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	79/185 (43%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
Iqsec1	XP_038964676.1	Sec7	612..800	CDD:396096	79/187 (42%)
		IQ_SEC7_PH	832..967	CDD:406773

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910