DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and fbxo8

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	NP_001035397.1	Gene:	fbxo8 / 678549	ZFINID:	ZDB-GENE-060421-7091	Length:	323	Species:	Danio rerio

Alignment Length:	181	Identity:	54/181 - (29%)
Similarity:	94/181 - (51%)	Gaps:	13/181 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 QMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKA 462
            ::..|...||.:|::||.|.:...:|...|:::|.|::....||...:..||.|:    .|||..
Zfish   142 ELDEGSLTFNANPQEGISYFMSRGILVEHPKEIAKFIFYTRMLNWKMLRIYLDER----RDVLDE 202

  Fly   463 FVALHDFTNLILVQALRQFLWSFRLPGE-AQKIDRMMETFAQRYCQLNP----DIFTNTDTCYVL 522
            .|.||:|:|..|..|||.|......|.| .:.::.::..|:.|:|..||    ::..:.|..|||
Zfish   203 LVTLHNFSNQFLPNALRDFFRHIHAPEERGEYLETLITKFSHRFCACNPALVQEVGLSPDAVYVL 267

  Fly   523 SFAIIMLNTSLHNPSVKDKPTVDQFI-SMNRGINNGGDLPRGLLESLYESI 572
            .:::|:|:..|.:|.||:|.:..:|| :..|...|   :....:..||::|
Zfish   268 CYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQN---ISEDFVGHLYDNI 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	54/181 (30%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
fbxo8	NP_001035397.1	F-box-like	78..116	CDD:315592
fbxo8	NP_001035397.1	Sec7	141..316	CDD:238100	54/181 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920