Protein Alignment step and RASA2

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_016862457.1
• Gene: RASA2 / 5922
• HGNCID: 9872
• Length: 872
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 84/425 - (19%)
• Similarity: 158/425 - (37%)
• Gaps: 128/425 - (30%)

  Fly   325 NNNNDSKRE---SQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDV 386
            |.|..||.:   |.:.|:|.:...:|...|....::   ::|:.|..|       .:|...|..:
Human   318 NGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKT---LLLKSPDVQ-------PISASAAYIL 372

  Fly   387 PEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGL--------NKT 443
            .|.|:..| |..:.:.|...:.|........|....|: |.|| |:.:::|..|        .|.
Human   373 SEICRDKN-DAVLPLVRLLLHHDKLVPFATAVAELDLK-DTQD-ANTIFRGNSLATRCLDEMMKI 434

  Fly   444 AIGDYL---------------------------GEKNDFNEDVLKAFVALHD--FTNLI------ 473
            ..|.||                           |:..:.|::.|:.:|   |  |..::
Human   435 VGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYV---DKLFNTIVKSSMSC 496

  Fly   474 ------LVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTS 532
                  :..:||| :.:.|.|.:..          .:|..::..:|       :..||:.:::..
Human   497 PTVMCDIFYSLRQ-MATQRFPNDPH----------VQYSAVSSFVF-------LRFFAVAVVSPH 543

  Fly   533 L-----HNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDG-------- 584
            .     |:|..:...|:.......:.:.:.|.|.:. ..|..|:...|.||:.|::|
Human   544 TFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKS-KSSFKETFMCEFFKMFQEEGYIIAVKKF 607

  Fly   585 ---------------NDLMHTFFNPDKEGWLWKQG-GR----YKSWKRRWFILNDNCLYYFEYTT 629
                           ::.:|.     |||.::|:. ||    .|::|:|||.|....|.|.:...
Human   608 LDEISSTETKESSGTSEPVHL-----KEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHKQPG 667

  Fly   630 DKEPRGIIPLENI-SVREIHDRS--KPHCFELFAT 661
            .|:....||::|| :|.::.:.|  |.:.|::..|
Human   668 SKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHT 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	37/233 (16%)
		PH_GRP1-like	592..710	CDD:269954	24/78 (31%)
		PH	596..708	CDD:278594	24/74 (32%)
RASA2	XP_016862457.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910