Protein Alignment step and cyth2

DIOPT Version :10

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_005157903.1
• Gene: cyth2 / 569358
• ZFINID: ZDB-GENE-100921-55
• Length: 416
• Species: Danio rerio
• Alignment Length: 388
• Identity: 254/388 - (65%)
• Similarity: 310/388 - (79%)
• Gaps: 13/388 - (3%)

  Fly   348 DRNYI----NTEQSDNLVILRRPS-------KQIKDELCEVVSEMEALDV-PEDCKHSNKDKQMS 400
            |.:||    :.|:...|..:||..       :::|:||.|.:.|:|.|:. .|..|...|.:.::
Zfish    19 DLDYIPADLSPEERSELEEIRRRKGALLLEIQRLKEELREAIIEVEGLETSTEGSKTLQKSRHVA 83

  Fly   401 IGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVA 465
            :|||||||||||||.:||||.||||.|:|:|.|||||||||||||||||||::|||..||:|||.
Zfish    84 MGRKKFNMDPKKGIVFLVENELLRHTPEDIAQFLYKGEGLNKTAIGDYLGERDDFNIKVLQAFVD 148

  Fly   466 LHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLN 530
            ||:||:|.||||||||||||||||||||||||||.||||||..||.:|.:|||||||||||||||
Zfish   149 LHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCHCNPGVFQSTDTCYVLSFAIIMLN 213

  Fly   531 TSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPD 595
            ||||||:|:|||||::|||||||||:|||||..||.:||:||:.||||||:||||||.|||||||
Zfish   214 TSLHNPNVRDKPTVERFISMNRGINDGGDLPEELLRNLYDSIKNEPFKIPEDDGNDLTHTFFNPD 278

  Fly   596 KEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFA 660
            :||||.|.|||.|:||||||||.|||||||||||||||||||||||:|:||:.|..||:||||:.
Zfish   279 REGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYI 343

  Fly   661 TGG-ADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKK 722
            ... ..:||||||:::|:||||.|.|||:||.|.|::.|||..:..::|.:|||::|..|||:
Zfish   344 PNNRGQLIKACKTEADGRVVEGNHMVYRISAPTPEEKDEWIHSIKSAVSVDPFYEMLAARKKR 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	395..577	CDD:460178	140/181 (77%)
		PH_GRP1-like	592..710	CDD:269954	77/118 (65%)
cyth2	XP_005157903.1	Sec7	78..260	CDD:460178	140/181 (77%)
		PH_GRP1-like	275..394	CDD:269954	77/118 (65%)