Protein Alignment step and farp2

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_009300696.1
• Gene: farp2 / 567490
• ZFINID: ZDB-GENE-030131-2993
• Length: 1051
• Species: Danio rerio
• Alignment Length: 644
• Identity: 117/644 - (18%)
• Similarity: 211/644 - (32%)
• Gaps: 222/644 - (34%)

  Fly   158 PY---TSVATYNITKLAPDSP--------------PPASPTLSTQTVNCSDVTTKVTEVQRLPCD 205
            ||   .|....:...||.|.|              ||:|.|.|.|:::...|:.:        .:
Zfish   371 PYQRRNSKIRMSTRSLASDVPKQNLSFNDSLRTHIPPSSITASFQSLHAPSVSMR--------AE 427

  Fly   206 EPNTELISKRTEY---------KHTTITTTTR-------TLIVSRPVELLLNENGEIIARRSPRK 254
            .||..|...:|::         |...|.|.::       ::.:..|.....|:.|.:....|.:.
Zfish   428 TPNQLLHLHQTQHQPLRAPSPMKQDPIKTNSQSTYAFPDSIAIDSPQLSPFNDKGPLCLSPSFQM 492

  Fly   255 SRSNSLGR-----MLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDSSNSQSESERNSN 314
            |..:..|:     ...:.||:||..|
Zfish   493 STLSLPGQAPSPLQSPILNEVGTARL--------------------------------------- 518

  Fly   315 IHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVS 379
                          |...|.::.      |...|:.|...::     ||......:||  .||::
Zfish   519 --------------DEDEEGRRK------RYPTDKAYFIAKE-----ILTTERTYLKD--LEVIT 556

  Fly   380 EMEALDVPEDCKHSNKDKQMSIGRKKF---NMDP----KKGIEYLVENRLLRHDPQDVAHFLYKG 437
            ......|       .|:..|..|....   |:||    .:|....::.||...:.:..||  .||
Zfish   557 VWFRSAV-------IKENAMPEGLMTLLFSNIDPIYEFHRGFLKEIDQRLALWEGRSNAH--VKG 612

  Fly   438 EGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLI---------LVQALRQFLWSFRLPGEAQK 493
            :   ...|||.:          |:...:|.:||..:         |.:|.::          .:|
Zfish   613 D---YQRIGDVM----------LRNMCSLKEFTGYLQKHDEVLTELEKATKR----------VKK 654

  Fly   494 IDRMMETF-AQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLH-NPSVKDKPTVDQFISMNRGINN 556
            ::.:.:.| .|:.|.|..:.|.......::.:.:|:.....| :|..:|      :......:..
Zfish   655 LETVYKEFELQKVCYLPLNTFLLKPIQRLMHYKLILERLCKHYSPQHRD------YDDCKEALKE 713

  Fly   557 GGDLPRGLLESLYESIRTEPFKIPQDDGNDL--MHTFFNPDKEGWLWKQGGRYKSWK-----RRW 614
            ..::...|..||   ||.|.|:...:...||  :.....|.:|  ..::|..||..|     |.:
Zfish   714 VAEIATQLQSSL---IRLENFQKLTELQRDLIGIENLTAPGRE--FIREGCLYKLTKKGLQQRMF 773

  Fly   615 FILNDNCLYYFE---YTTDKEPRGIIPLENI-------SVREIHDR-SKPHCFELFATGGADIIK 668
            |:.:|..||..:   .|...:..|.:||..:       .|.|..:. |.||||.:::
Zfish   774 FLFSDMLLYTSKGVTATNQFKVHGQLPLHGMILIVLDAPVEESENEWSVPHCFTIYS-------- 830

  Fly   669 ACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALSKS 727
                        .:.|:. ::|:::.:..:||:.|..:|          :..||...||
Zfish   831 ------------AQRTIV-VAASSKVEMNKWIEDLNMAI----------EMSKKCQEKS 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	37/197 (19%)
		PH_GRP1-like	592..710	CDD:269954	28/133 (21%)
		PH	596..708	CDD:278594	26/127 (20%)
farp2	XP_009300696.1	B41	53..241	CDD:214604
		FERM_N	55..118	CDD:286467
		FERM_M	138..241	CDD:278785
		FERM_C_FARP1-like	228..348	CDD:270014
		FA	341..382	CDD:285894	3/10 (30%)
		RhoGEF	537..720	CDD:279015	39/227 (17%)
		PH1_FARP1-like	747..861	CDD:269928	28/146 (19%)
		PH	755..857	CDD:278594	26/132 (20%)
		PH2_FARP1-like	933..1030	CDD:270055
		PH	938..1031	CDD:278594

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910