DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and si:dkey-191m6.4

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	XP_683216.5	Gene:	si:dkey-191m6.4 / 555573	ZFINID:	ZDB-GENE-121214-182	Length:	696	Species:	Danio rerio

Alignment Length:	115	Identity:	34/115 - (29%)
Similarity:	58/115 - (50%)	Gaps:	15/115 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 KEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREI-HDRSKP--HCFE 657
            |.|||.||....|:|:.|||:|..:.|::::...:.:|:|.|.|:...|.|: .:..:|  |.||
Zfish    43 KAGWLKKQRSIMKNWQLRWFVLRADHLFFYKDEEETKPQGCISLKGSQVNELTANPEEPGRHLFE 107

  Fly   658 LFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSI 707
            :...|..|  ||..:          |..:.:.|.|:.|..:|:|.:.:.|
Zfish   108 ILPAGEKD--KAAMS----------HESFLLMANTQSDMDDWVKAIRRVI 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680
		PH_GRP1-like	592..710	CDD:269954	34/115 (30%)
		PH	596..708	CDD:278594	34/115 (30%)
si:dkey-191m6.4	XP_683216.5	PH-like	39..152	CDD:302622	34/115 (30%)
		PH	41..145	CDD:278594	33/113 (29%)
		RhoGAP_ARHGAP22_24_25	152..350	CDD:239855
		GBP_C	<601..680	CDD:303769
		coiled coil	651..662	CDD:293879
		coiled coil	670..680	CDD:293879
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910