DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and uqcrfs1

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	NP_988911.1	Gene:	uqcrfs1 / 394506	XenbaseID:	XB-GENE-5746219	Length:	273	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	49/286 - (17%)
Similarity:	88/286 - (30%)	Gaps:	119/286 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 RSPSMAPYTSVATYNIT-KLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKR 215
            ||.|:|||.|..:|.:. :|.|                                      |:|.
Frog     7 RSGSVAPYLSATSYAVAGQLKP--------------------------------------LVSG- 32

  Fly   216 TEYKHTTITTTTRTLIVSRPVELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEAD 280
                           :|.:..::||:.....:.|.|              :..:...|||...|.
Frog    33 ---------------VVLQADKVLLDVKKPFLCRES--------------LNGQAPNGGLSASAG 68

  Fly   281 ----PCSK---NSLPPPPYIDDMR--FIDDSSNSQSESERNSNIH------------------KT 318
                .|.:   :.:..|.:.|..|  .:|.:.:||:.|:...:..                  .|
Frog    69 INGAACVRFLHSDVTVPDFSDYRRPEVLDSTKSSQTSSDSRKSFSYLVTGVTAVATAYAAKNAVT 133

  Fly   319 NKYTSKNNNND----SKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVS 379
            ...||.:.:.|    ||.|.:.|::.|.      :|.....:...|.:..|.:|:|..|     :
Frog   134 QFVTSMSASADVLAMSKIEIKLSDIPEG------KNMAFKWRGKPLFVRHRTAKEIDQE-----A 187

  Fly   380 EMEALDVPEDCKHSNKDKQMSIGRKK 405
            ::...|:        :|.|..:.|.|
Frog   188 QVNLTDL--------RDPQHDLDRVK 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	3/9 (33%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
uqcrfs1	NP_988911.1	Ubiq-Cytc-red_N	2..76	CDD:370333	22/136 (16%)
		UCR_TM	79..144	CDD:367251	10/64 (16%)
		Rieske_cytochrome_bc1	150..273	CDD:239552	15/75 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910