Protein Alignment step and mon2

DIOPT Version :10

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_001033884.2
• Gene: mon2 / 326157
• FlyBaseID: FBgn0031985
• Length: 1684
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 111/622 - (17%)
• Similarity: 182/622 - (29%)
• Gaps: 244/622 - (39%)

  Fly   188 NCSD---------VTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRPVELLLNEN 243
            |.||         ::|::.:|..|| |.|.|   .|..::....:              .|..:.
  Fly   952 NISDFFNQNQDKLMSTQLQDVSILP-DFPGT---VKMPQFDKLWM--------------CLYAKL 998

  Fly   244 GEIIA--RRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPP-----------PYIDD 295
            ||:..  |.:.|||...:|...:.....:                |.||           |.:|:
  Fly   999 GELCVDLRPAVRKSAGQTLFSTISAHGSL----------------LNPPTWQALVWQVLFPLLDN 1047

  Fly   296 MRFIDDS-SNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDN 359
            :|.:..| ||.:.::..|..||.     |:|.......|:|...|...||:      .||
  Fly  1048 VRALSSSASNEKVDASGNILIHH-----SRNTAQKQWAETQVLTLSGVCRV------FNT----- 1096

  Fly   360 LVILRRPSKQIKDELCEVVSEME-----ALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVE 419
                       |.||.:::.:.|     .|:..::...| |:.::|:...|...      |.:..
  Fly  1097 -----------KRELLQMLGDFERAWSLILEFIQNAALS-KNGEVSLAALKSLQ------EIMYH 1143

  Fly   420 N------RLLRHDPQ----------DVAHFLYKGEGLNKTAIGD----YLGEKNDFNEDVLKAFV 464
            |      |.|: |||          .:|..::...|:..|.:..    .|.::|....:..:.|.
  Fly  1144 NTAERTERALK-DPQTAQEQDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFY 1207

  Fly   465 ALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTC-YVLSFAIIM 528
            .........|:|.........::...|...|:.........|     |...||.. |::|.....
  Fly  1208 IPSQAFLTALIQIFPAIFQHIQVKFTAADFDKFCTVLTNAVC-----IPVQTDAVPYIMSTVSDT 1267

  Fly   529 LNTSLHN------------------------PSVKDK-----------PTVDQFI------SMNR 552
            |.|.||:                        |::..:           ||..|.:      |...
  Fly  1268 LLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSGH 1332

  Fly   553 GINNG------------GDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQGG 605
            ..||.            |:....:...||::..||...:.:...:|::.....|        ...
  Fly  1333 YANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDIVKALRTP--------LAM 1389

  Fly   606 RYK-----SWK-------------------------RRWFILNDNCLYYFEYTTDK--------- 631
            :||     :||                         ..|..|.|        |.||
  Fly  1390 KYKCLSSSTWKLAISSLISVLHTGLKVARAKPQHFASLWDDLAD--------TLDKFLFPASVCT 1446

  Fly   632 -EPRGIIPLENISVRE---------IHDRSKPHCFEL 658
             |.||   ||.|.:.|         :.|...||..|:
  Fly  1447 IEDRG---LEEIVLDETIDCQVIELLRDEVLPHSHEM 1480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	395..577	CDD:460178	42/255 (16%)
		PH_GRP1-like	592..710	CDD:269954	22/116 (19%)
mon2	NP_001033884.2	DCB	13..181	CDD:465072
		Sec7_N	213..380	CDD:463703
		DUF1981	827..909	CDD:462756
		Mon2_C	912..1665	CDD:465066	111/622 (18%)