DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and Gbf1

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	XP_006231558.1	Gene:	Gbf1 / 309451	RGDID:	1307160	Length:	1895	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	77/232 - (33%)
Similarity:	131/232 - (56%)	Gaps:	21/232 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   375 CEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLR--HDPQDVAHFLYKG 437
            |.:....|.:::      .||.|.:..|.::||..|||||::|.|..||.  .|..:||.:|.:.
  Rat   719 CLLPDPRELIEI------KNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLREN 777

  Fly   438 EGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFA 502
            ..|:|..||:::.::.  |.|:|::||:...|..|.|.:|||.:|.:|||||||..|.|::|.|.
  Rat   778 PRLDKKMIGEFVSDRK--NMDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIHRLLEVFT 840

  Fly   503 QRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDK---PTVDQFISMNRGINNGGDLPRGL 564
            :.:...|...|.|:|.|:.|::|:|||||..||.:|:.:   .|:::|....:|:|.|.|..:.:
  Rat   841 EHWRSCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDI 905

  Fly   565 LESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLW 601
            ||.:|.:|:.|...:|::....:        :|.::|
  Rat   906 LEDMYHAIKNEEIVMPEEQTGLV--------RENYVW 934

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	70/184 (38%)
		PH_GRP1-like	592..710	CDD:269954	2/10 (20%)
		PH	596..708	CDD:278594	2/6 (33%)
Gbf1	XP_006231558.1	Sec7_N	434..579	CDD:289549
Gbf1	XP_006231558.1	Sec7	733..918	CDD:279680	71/186 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820