DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment step and Psd2

DIOPT Version :9

Sequence 1:NP_001036375.2 Gene:step / 35425 FlyBaseID:FBgn0086779 Length:727 Species:Drosophila melanogaster
Sequence 2:XP_006254639.1 Gene:Psd2 / 307500 RGDID:1311075 Length:772 Species:Rattus norvegicus


Alignment Length:443 Identity:111/443 - (25%)
Similarity:187/443 - (42%) Gaps:93/443 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   349 RNYINTEQSDN----LVILRRPSKQIKDE-------------LCEVVSEMEALDVPEDCKHSNKD 396
            |..|::.:|:|    |.:...|:...:||             ..:|::......:.:....|:.:
  Rat   222 RRSISSSRSENVLSHLSLTSMPNGFHEDEPGGSGGDDEDDEDTDKVLNSASDTSLKDGLSDSDSE 286

  Fly   397 KQMSIGRKKFNMDP-KKGIEYLVE--NRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNED 458
            ...|.|.:..:.|| ..|.:.:.|  .||.|.        ||..||..:..:...||:.|:|:..
  Rat   287 LSSSEGLEPGSTDPMANGCQGVSEAARRLARR--------LYHLEGFQRCDVARQLGKNNEFSRL 343

  Fly   459 VLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLS 523
            |...:::..||:.|.|.:|||.||.:|.|.||.|:.:|::..|::||||.|||..|:.|..:.|:
  Rat   344 VAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLT 408

  Fly   524 FAIIMLNTSLH-NPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDG--- 584
            .|:::|||.|| :.::..|.:..|||:....:|:|.|..:.||::||.||:.|..:...|:.   
  Rat   409 CALMLLNTDLHGHVNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELR 473

  Fly   585 ---NDLMHTFF--------------NP------------------------DKEGWLWKQGGRYK 608
               ::|:...|              ||                        |.:|....:|.|  
  Rat   474 KSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRR-- 536

  Fly   609 SWKRRWFILNDNCLYY--FEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACK 671
            .||:.:.:|....||.  .||..||.         :|..::.:..:.|  ...||..:|.   .|
  Rat   537 GWKKFYAVLKGTILYLQKDEYRPDKA---------LSEGDLKNAIRVH--HALATRASDY---SK 587

  Fly   672 TDSEGKVVEGKHTVYRMSAATEEDQQEWIKR--LTQSISHNPFYDILVQRKKK 722
            ..:..|:......|:...|.::|:...||.|  |..:|...|.:...|...||
  Rat   588 KSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKK 640

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stepNP_001036375.2 Sec7 397..577 CDD:279680 64/183 (35%)
PH_GRP1-like 592..710 CDD:269954 31/159 (19%)
PH 596..708 CDD:278594 26/115 (23%)
Psd2XP_006254639.1 Sec7 295..463 CDD:238100 62/175 (35%)
PH_EFA6 509..632 CDD:270107 29/138 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5307
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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