Protein Alignment step and Appl1

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_038951064.1
• Gene: Appl1 / 290537
• RGDID: 1309388
• Length: 720
• Species: Rattus norvegicus
• Alignment Length: 441
• Identity: 76/441 - (17%)
• Similarity: 159/441 - (36%)
• Gaps: 143/441 - (32%)

  Fly   307 SESERNSNIHKTNK----YTSKNNNNDSKRESQQSNL---------CESCRMLLDRNYINTEQSD 358
            :::|.::..|.|:|    |..:........|...|.|         ..||..:|     :|:.:|
  Rat    50 AQNELSAATHLTSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVL-----STQLAD 109

  Fly   359 NLVILRRPSKQIKD-ELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRL 422
            .::.   |..|.|: :|.|:::..|...:      ::.|...:|.|  ::...||.     ||..
  Rat   110 AMMF---PISQFKERDLKEILTLKEVFQI------ASNDHDAAINR--YSRLSKKR-----ENDK 158

  Fly   423 LRHD-PQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDF---TNLILVQALRQFLW 483
            :::: .:||                 |...|.. ::.::..|.||:..   ..:.|::.|..::.
  Rat   159 VKYEVTEDV-----------------YTSRKKQ-HQTMMHYFCALNTLQYKKKIALLEPLLGYMQ 205

  Fly   484 S----FRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTV 544
            :    |::..|  .::..:|.|                        :..:.||:.|
  Rat   206 AQISFFKMGSE--NLNGQLEEF------------------------LANIGTSVQN--------- 235

  Fly   545 DQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWL---WKQGGR 606
                 :.|.::...:..:..:|.|  .:.::|..:|..|............|.|:|   .|.|..
  Rat   236 -----VRREMDGDVETMQQTIEDL--EVASDPLYLPDPDPTKFPVNRNLTRKAGYLNARNKTGLV 293

  Fly   607 YKSWKRRWFILNDNCLYYFEYTTDKEPRG------IIPLENISVREIHDRSKPHCFELFATGGAD 665
            ..:|.|:::......|.       .:.||      .:.::|.||..:....:.:||::
  Rat   294 SSTWDRQFYFTQGGNLM-------SQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQI------- 344

  Fly   666 IIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEW---IKRLTQSI--SHNP 711
                  |..:||    |.::  :.|.:::|.:||   |..:::.|  |.||
  Rat   345 ------TSFDGK----KSSI--LQAESKKDHEEWICTINNISKQIYLSENP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	25/187 (13%)
		PH_GRP1-like	592..710	CDD:269954	26/131 (20%)
		PH	596..708	CDD:278594	25/125 (20%)
Appl1	XP_038951064.1	BAR_APPL1	20..234	CDD:153315	41/248 (17%)
		BAR-PH_APPL	252..376	CDD:270067	29/151 (19%)
		PTB_APPL	506..637	CDD:269980

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910