Protein Alignment step and ACAP2

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_016861535.1
• Gene: ACAP2 / 23527
• HGNCID: 16469
• Length: 848
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 86/471 - (18%)
• Similarity: 161/471 - (34%)
• Gaps: 152/471 - (32%)

  Fly   270 IGTGGLFMEADPCSKNSLPP-PPYIDDMRFIDDSSNSQSES-ERNSNIHKTNKYTSKNNNNDSKR 332
            |.||..|..|:....|.:.. ..|..:...::.|....|:| :...|.|              .|
Human    46 IDTGKAFCVANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFH--------------TR 96

  Fly   333 ESQQSNLCESCR-----MLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKH 392
            :....:|...||     :|.:.:::      .:::..:..:.||.:|...|.|    |:
Human    97 QGLPLSLRLECRGMIIALLWESSHL------RMILFDQTQRSIKAQLQNFVKE----DL------ 145

  Fly   393 SNKDKQMSIGRKKFNMDPKKGIEYLVEN----RLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKN 453
                ::....:|:|....::....||:|    |..:|:.::..:.|.......:....||:.:.|
Human   146 ----RKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQIN 206

  Fly   454 DF----NEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFT 514
            ..    ..::||:.::               |:::.            :..|.|.|     |:|:
Human   207 VLQSKRRSEILKSMLS---------------FMYAH------------LAFFHQGY-----DLFS 239

  Fly   515 NTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEP--F 577
            ..                  .|.:||.               |..|.|.::::..|....|.  .
Human   240 EL------------------GPYMKDL---------------GAQLDRLVVDAAKEKREMEQKHS 271

  Fly   578 KIPQDD-GNDLMHTFFNPD------KEGWLWKQGGR-YKSWK-------RRWFILNDNCLYYFEY 627
            .|.|.| .:|.....:|.|      .||:|:|:... :|:|.       ||||.:.:|.|.|.:.
Human   272 TIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRKKPDHIRRWFSIQNNQLVYQKK 336

  Fly   628 TTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAAT 692
            ..|.....:..|...:|:...|..:..|||:.:.     .|:|                .:.|.:
Human   337 FKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSP-----TKSC----------------MLQADS 380

  Fly   693 EEDQQEWIKRLTQSIS 708
            |:.:|.|||.:..||:
Human   381 EKLRQAWIKAVQTSIA 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	27/189 (14%)
		PH_GRP1-like	592..710	CDD:269954	32/131 (24%)
		PH	596..708	CDD:278594	29/119 (24%)
ACAP2	XP_016861535.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910