Protein Alignment step and PSD3

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_016868747.1
• Gene: PSD3 / 23362
• HGNCID: 19093
• Length: 1067
• Species: Homo sapiens
• Alignment Length: 809
• Identity: 162/809 - (20%)
• Similarity: 278/809 - (34%)
• Gaps: 256/809 - (31%)

  Fly    38 GRKQPL---QRSC--LDLSTTRVGCDGCVSLEFFQSE--------------SPESRRSNSTFYVN 83
            |||..:   :.||  ..|.::.|.|....|:.|.:.:              |....|.....:|.
Human   256 GRKGAVCVQEPSCPLASLGSSAVTCHSAGSVGFLKEQRSALGREHPGGCDRSSSMGRPGRVKHVE 320

  Fly    84 TQNV----SSAVFKDNRQPL-----LERGSGSDSSPSSVCVR--------CSCNSITKS-GDRNE 130
            .|.|    :....::.:.|:     |:|.:..||..||...|        |:.:|:|:: .|.:.
Human   321 FQGVEILWTGGDKRETQHPIDFETSLQRTASPDSKESSKVPRHLISSAGLCNSSSLTENVWDESW 385

  Fly   131 TPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTK 195
                                 ::||..|.||..|::..:|............:.|
Human   386 ---------------------KAPSERPGTSSGTFSPVRLDESGEDEVFLQENKQ---------- 419

  Fly   196 VTEVQRLPCDEPNTELISKRTEY-----------------------KHTTITTTTRTLIVSRPVE 237
              .:::.|..|.:.|.||::.|:                       :..||...|.....:..:|
Human   420 --HLEKTPKPERDRERISEQEEHVKGEDEDILGPGYTEDSTDVYSSQFETILDNTSLYYSAESLE 482

  Fly   238 LLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDS 302
            .|.:|.....:...|       |..|  :|..|..||.|:|.
Human   483 TLYSEPDSYFSFEMP-------LTPM--IQQRIKEGGQFLER----------------------- 515

  Fly   303 SNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYIN--TEQSDNLVILRR 365
                               ||...:.|....|....:.    |.......|  .:.||::.....
Human   516 -------------------TSGGGHQDILSVSADGGIV----MGYSSGVTNGLNDASDSIYTKGT 557

  Fly   366 P-------SKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLL 423
            |       :..:|....|..|||.:.::.|    ....:.:|.|... |::..|        ||.
Human   558 PEIAFWGSNAGVKTTRLEAHSEMGSTEILE----KETPENLSNGTSS-NVEAAK--------RLA 609

  Fly   424 RHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLP 488
            :.        ||:.:...::.:..:||:.|:|::.|.:.::...|||.:.|.|:||.|..:|.|.
Human   610 KR--------LYQLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLV 666

  Fly   489 GEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRG 553
            ||.|:.:|::..|:.||...|||...:.|..:.|:.||::|||.||..::..|.|..:||:..:|
Human   667 GETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQG 731

  Fly   554 INNGGDLPRGLLESLYESIR---------------------------------------TEPF-K 578
            :|.|.|..:.||::||.||:                                       |.|| .
Human   732 VNEGVDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISRIGSTTNPFLD 796

  Fly   579 IPQDDGNDLMHTFF-----NPDKEGWLWKQGGRYKSWKRRWFILNDNCLYY--FEYTTDK----- 631
            ||.|....:..:.|     :.|.:|....:|.|  .||..:.:|....||.  .||..:|
Human   797 IPHDPNAAVYKSGFLARKIHADMDGKKTPRGKR--GWKTFYAVLKGTVLYLQKDEYKPEKALSEE 859

  Fly   632 EPRGIIPLENISVREIHD-RSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEED 695
            :.:..:.:.:....:..| ..||:.|:|                  |..:.:  |......:.|:
Human   860 DLKNAVSVHHALASKATDYEKKPNVFKL------------------KTADWR--VLLFQTQSPEE 904

  Fly   696 QQEWIKRL---TQSISHNPFYDILVQRKK 721
            .|.||.::   ....|..||...:..:||
Human   905 MQGWINKINCVAAVFSAPPFPAAIGSQKK 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	57/218 (26%)
		PH_GRP1-like	592..710	CDD:269954	25/133 (19%)
		PH	596..708	CDD:278594	22/122 (18%)
PSD3	XP_016868747.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810