Protein Alignment step and Cyth1

DIOPT Version :10

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_001106170.1
• Gene: Cyth1 / 19157
• MGIID: 1334257
• Length: 400
• Species: Mus musculus
• Alignment Length: 383
• Identity: 252/383 - (65%)
• Similarity: 315/383 - (82%)
• Gaps: 9/383 - (2%)

  Fly   352 INTEQSDNLVILRRPSKQ-------IKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMD 409
            :..|:...|..:||..::       :|:|:.||.:|:|:|...|:.|:..::||:::||||||||
Mouse    14 LTAEERQELENIRRRKQELLADIQRLKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMD 78

  Fly   410 PKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLIL 474
            |||||::|:||.||::..:|:|.|||||||||||||||||||:::|:..||.|||.||:||:|.|
Mouse    79 PKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNL 143

  Fly   475 VQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVK 539
            |||||||||||||||||||||||||.|||||||.|..:|.:|||||||||||||||||||||:||
Mouse   144 VQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVK 208

  Fly   540 DKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWK-Q 603
            |||||::||:||||||:|||||..||.:|||||:.||||||:||||||.|||||||:||||.| .
Mouse   209 DKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLG 273

  Fly   604 GGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGAD-II 667
            |||.|:||||||||.|||||||||||||||||||||||:|:||:.|..||:||||:.....| :|
Mouse   274 GGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVI 338

  Fly   668 KACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALS 725
            |||||:::|:||||.|||||:||.|.|::::|||.:..:||.:|||::|..||||..|
Mouse   339 KACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	395..577	CDD:460178	136/181 (75%)
		PH_GRP1-like	592..710	CDD:269954	80/119 (67%)
Cyth1	NP_001106170.1	Sec7	64..246	CDD:460178	136/181 (75%)
		PH_GRP1-like	261..381	CDD:269954	80/119 (67%)