Protein Alignment step and bris-1

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_500420.3
• Gene: bris-1 / 177142
• WormBaseID: WBGene00019726
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 118/491 - (24%)
• Similarity: 182/491 - (37%)
• Gaps: 157/491 - (31%)

  Fly   107 DSSPSSVCVRCSCNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLA 171
            |:.|..:..||.    ..:..|||....:...:.:...|:.....||              |.|.
 Worm    74 DTIPDHLDARCG----VSNSQRNELSLTSRYATSLSAQLRIDRAARS--------------TTLD 120

  Fly   172 PDSPPPASPTL-STQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRP 235
            ...|.||.|.| :.|..|..|                  .|:|.|
 Worm   121 RSPPSPAPPVLVNLQNSNMID------------------SLMSPR-------------------- 147

  Fly   236 VELLLNEN-GEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFI 299
               |.|.. |...:|.:|..:...|....|...:       .:..:|...|||   |.:|..|..
 Worm   148 ---LGNRRFGAAASRCAPAAAELTSTEVWLPRPS-------LVNHNPAHSNSL---PRLDKHRVH 199

  Fly   300 D--DSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVI 362
            :  :|||.:.:||
 Worm   200 ERSESSNGRKKSE---------------------------------------------------- 212

  Fly   363 LRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDP 427
             .:|.:|:.|:                    .:.:|..|....||..|::|::.|.....:::.|
 Worm   213 -VKPPRQMTDQ--------------------ERKRQYRIALNFFNKKPERGVQLLTAWGFVKNSP 256

  Fly   428 QDVAHFLYKGEGLNKTAIGDYLGE-KNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEA 491
            ..:|..|:...||:|:.||:|:|. .:.::..|||.|.||.|...|.:..|||:.:..|.||.||
 Worm   257 DSLASLLFGRRGLSKSMIGEYIGTLHSPYHSLVLKYFTALIDIRGLEVDVALRKAMQFFILPKEA 321

  Fly   492 QKIDRMMETFAQRYCQLNPDIFTN----TDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNR 552
            :||||:::.||..|.:.||...::    .||.::||||||||||.||:|:||.:.|...|:...|
 Worm   322 EKIDRIIQAFALHYSKSNPKRTSHYRGGWDTIHLLSFAIIMLNTDLHSPNVKQRMTQADFVKNLR 386

  Fly   553 GIN------NGGDLPRGLLESLYESIRTEPFKIPQD 582
            |.:      ||.|:.|..||.:|:.|:.:..|...|
 Worm   387 GQDKISGEKNGEDIDRKTLEGIYDRIKKDELKAGDD 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	71/190 (37%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
bris-1	NP_500420.3	Sec7	224..417	CDD:366596	71/192 (37%)
		PH_IQSEC	445..573	CDD:270128

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910