Protein Alignment step and gbf-1

DIOPT Version :10

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_001366879.1
• Gene: gbf-1 / 176609
• WormBaseID: WBGene00007703
• Length: 1975
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 96/324 - (29%)
• Similarity: 146/324 - (45%)
• Gaps: 69/324 - (21%)

  Fly   391 KHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDF 455
            :...:.:.::.|.:.||..|||||.:|.|..:|.||.|.:..:|.....|:|.||.||:..:.
 Worm   627 EQKKRKRLIAEGTELFNQSPKKGIAFLREKGILGHDEQSLVQWLRTNPQLDKKAIADYICNRK-- 689

  Fly   456 NEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCY 520
            :.:||.|||....|.|..|..|||.||.:||||||:.:|..:|:.|::.:.:.|.:.|.:.|..:
 Worm   690 HAEVLNAFVKSFPFENTRLDVALRMFLETFRLPGESAEIALVMQHFSEEWFRANNEPFFHVDAAF 754

  Fly   521 VLSFAIIMLNTSLHNPSVK-DKP--TVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQD 582
            .||:||||||...|||..| .:|  |||.|.....|.|:..|....:|..:|::|:||...:|.:
 Worm   755 TLSYAIIMLNVDQHNPQAKRSQPPMTVDCFRRNLSGTNDSRDFDPEMLADMYQAIKTEEIVMPAE 819

  Fly   583 DGNDLMHTFFNPDKEGWLWK---------QGGRYKS---WKRRWFILNDNCLY---------YFE 626
            ....:        ||.::||         :|..|.:   |       ||:.|:         ...
 Worm   820 QKGTV--------KEDYMWKVLLRRGETAEGSFYHAPTGW-------NDHDLFAVCWGPAVAALS 869

  Fly   627 YTTDKEPRGIIPLENIS-------------VREIHDRSKPHCFEL--FAT----------GGAD 665
            |..||.....|..:.::             ::|:.|..   |..|  |.|          ||||
 Worm   870 YVFDKSEHEQILQKALTGYRKCAKIAAYYGMKEVFDNL---CIHLCKFTTLTSMRDGGAGGGAD 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	395..577	CDD:460178	71/184 (39%)
		PH_GRP1-like	592..710	CDD:269954	24/120 (20%)
gbf-1	NP_001366879.1	PLN03076	<383..>1144	CDD:215560	96/324 (30%)
		Sec7	631..814	CDD:460178	71/184 (39%)
		PLN03209	<1696..1810	CDD:178748