DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and AgaP_AGAP006510

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	XP_316537.2	Gene:	AgaP_AGAP006510 / 1277104	VectorBaseID:	AGAP006510	Length:	538	Species:	Anopheles gambiae

Alignment Length:	202	Identity:	38/202 - (18%)
Similarity:	71/202 - (35%)	Gaps:	62/202 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 KHSNKDKQMSIGRKKFNMDPKKG--IEY------LVENR----LLRHDPQDVAHFLYKGEGLNKT 443
            ||:|.....|    ::..||.:|  |::      ::..|    |..|:.:.:...||......:|
Mosquito    38 KHNNGGSIDS----RYTPDPNRGQLIKHPKGGVDIIRPRTTPLLPGHNTRRIVVALYNYNAREET 98

  Fly   444 AIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFL--WSFRLPG----------------E 490
            .:....|::.:..:|...      |:..::.::..::.|  |:|....                |
Mosquito    99 DVSFVKGDRMEVLDDTES------DWWRVVHLKTRQEGLIPWNFVAEDRSVNSEDWFFENVSRKE 157

  Fly   491 AQKI----DRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMN 551
            |.|:    :....||..|..:.||:.|:       ||......:...|....|.||
Mosquito   158 ADKLLLANENPRGTFLVRPSEHNPNGFS-------LSVKDWEESRGYHVKHYKIKP--------- 206

  Fly   552 RGINNGG 558
              ::|||
Mosquito   207 --LDNGG 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	35/196 (18%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
AgaP_AGAP006510	XP_316537.2	SH3_Src_like	85..136	CDD:212779	8/56 (14%)
		SH2_Src_family	144..244	CDD:199827	18/86 (21%)
		STYKc	270..522	CDD:214568
		PTKc_Src_like	274..522	CDD:270630
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910