Protein Alignment step and AgaP_AGAP002438

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_563746.4
• Gene: AgaP_AGAP002438 / 1273523
• VectorBaseID: AGAP002438
• Length: 643
• Species: Anopheles gambiae
• Alignment Length: 407
• Identity: 73/407 - (17%)
• Similarity: 129/407 - (31%)
• Gaps: 146/407 - (35%)

  Fly   196 VTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRPVELLLNENG---------------- 244
            :...:|.|..|....::..|..:..|.||...    ::..||.|..|||
Mosquito   186 IEHYKRNPMVETCGTVVHLRQPFNATRITAAG----INDRVEQLQRENGGQSYGKGGFWEEFESL 246

  Fly   245 ------EIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFI---- 299
                  ...:||..:::.:.:..|..::.....|.....:.|    :::|...|| :..:|
Mosquito   247 QQQECRHTFSRREGQRNENRAKNRYKNILPFDHTRVKLKDVD----STVPGADYI-NANYIRQPT 306

  Fly   300 ----DDSSNSQSESERNSNIHKTNKYTSKN--NNNDSKRESQQSNLCESCRMLLDRNYINTEQSD 358
                :|.|:|.....:::.....|.|:..|  |||.:...|       :|:.....:...|:...
Mosquito   307 EAEQNDMSSSSENLAQSAGSGLNNGYSQPNATNNNGTNGNS-------ACQGYSAGSVAPTKNCS 364

  Fly   359 NLVILRRP--------SKQIKDELCEVVSEMEALDVPEDCKHSNKD------------------- 396
            :..:|.:|        |.::|.:..|.::....|......|...||
Mosquito   365 SCQLLNKPCSQCSLKASSEMKHKRNESITSRMQLQQQSPHKRDEKDMFKTYIATQGCLTNTIQDF 429

  Fly   397 ----------------KQMSIGRK---KFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNK 442
                            |:|..|:|   |:..||::..|:              .|  .:...|::
Mosquito   430 WNMIWQENTRVIVMTTKEMERGKKKCEKYWPDPQQSKEW--------------GH--ARVRCLSE 478

  Fly   443 TAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQ 507
            |:..||                            .||:||.|:| ..|.:||       .|.:.|
Mosquito   479 TSTADY----------------------------TLREFLLSWR-GQEDRKI-------YQYHFQ 507

  Fly   508 LNPDIFTNTDTCYVLSF 524
            :.||.....|...||:|
Mosquito   508 VWPDHGVPADPGCVLNF 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	30/131 (23%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
AgaP_AGAP002438	XP_563746.4	SH2_N-SH2_SHP_like	8..105	CDD:198203
		SH2_C-SH2_SHP_like	113..210	CDD:198185	4/23 (17%)
		PTPc	238..610	CDD:214550	60/351 (17%)
		PTPc	268..609	CDD:238006	58/321 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910