Protein Alignment step and Cyth1

DIOPT Version :10

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_063124376.1
• Gene: Cyth1 / 116691
• RGDID: 620397
• Length: 400
• Species: Rattus norvegicus
• Alignment Length: 382
• Identity: 252/382 - (65%)
• Similarity: 315/382 - (82%)
• Gaps: 8/382 - (2%)

  Fly   352 INTEQSDNLVILRRPSKQ-------IKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMD 409
            :..|:...|..:||..::       :|:|:.||.:|:|:|...|:.|:..::||:::||||||||
  Rat    15 LTAEERQELENIRRRKQELLADIQRLKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMD 79

  Fly   410 PKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLIL 474
            |||||::|:||.||::..:|:|.|||||||||||||||||||:::|:..||.|||.||:||:|.|
  Rat    80 PKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNL 144

  Fly   475 VQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVK 539
            |||||||||||||||||||||||||.|||||||.|..:|.:|||||||||||||||||||||:||
  Rat   145 VQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVK 209

  Fly   540 DKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQG 604
            |||||::||:||||||:|||||..||.:|||||:.||||||:||||||.|||||||:||||.|.|
  Rat   210 DKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLG 274

  Fly   605 GRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGAD-IIK 668
            ||.|:||||||||.|||||||||||||||||||||||:|:||:.|..||:||||:.....| :||
  Rat   275 GRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIK 339

  Fly   669 ACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALS 725
            ||||:::|:||||.|||||:||.|.|::::|||.:..:||.:|||::|..||||..|
  Rat   340 ACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	395..577	CDD:460178	136/181 (75%)
		PH_GRP1-like	592..710	CDD:269954	80/118 (68%)
Cyth1	XP_063124376.1	None