DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and Plekha5

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	XP_006506926.1	Gene:	Plekha5 / 109135	MGIID:	1923802	Length:	1270	Species:	Mus musculus

Alignment Length:	168	Identity:	44/168 - (26%)
Similarity:	74/168 - (44%)	Gaps:	45/168 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   593 NPD----KEGWLWKQGGR-YKSWKRRWFILNDNCLYYFEYTTDKEPRGI-----IPLENISVREI 647
            ||:    :.|||:||... .|.||:|||:|:|.||:|:.   |::..||     :|...|::...
Mouse   166 NPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYR---DEKEEGILGSILLPSFQIAMLTA 227

  Fly   648 HDR-SKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEED--QQEWIKRL------ 703
            .|. ::.:.|:. |.........| ||:      ||.....|.|..:..  |.|.:||:
Mouse   228 EDHINRKYAFKA-AHPNMRTYYFC-TDT------GKEMELWMKAMLDAALVQTEPVKRITFNFRV 284

  Fly   704 ---------TQSISHNPFYDILVQ------RKKKALSK 726
                     |:..::.|.:.:|::      :|.|.:||
Mouse   285 DKITTDSASTKETNNIPNHRVLIRPEVQNHQKNKEISK 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680
		PH_GRP1-like	592..710	CDD:269954	38/144 (26%)
		PH	596..708	CDD:278594	36/135 (27%)
Plekha5	XP_006506926.1	WW	13..42	CDD:366073
		WW	59..88	CDD:366073
		PH_PEPP1_2_3	165..268	CDD:270068	33/112 (29%)
		Smc	<623..>864	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910