Protein Alignment step and arfgef2

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_002666513.2
• Gene: arfgef2 / 100334572
• ZFINID: ZDB-GENE-090312-50
• Length: 1846
• Species: Danio rerio
• Alignment Length: 629
• Identity: 167/629 - (26%)
• Similarity: 262/629 - (41%)
• Gaps: 141/629 - (22%)

  Fly     9 PSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVGCDGCVSLEFFQSESPES 73
            ||::.........|:    |....|||.:...:|  .|.|..|:...|.|        |....|:
Zfish   328 PSVTGGVEGEETHPQ----SETEAGSEVLEETEP--DSGLGDSSVEGGLD--------QHSDSET 378

  Fly    74 RRSNSTFYVNTQNVSSAVFKDNRQPLLERGSGSDSSPSSVCVRCSCNSITKSGDRN--ETPTMAT 136
            |.......|:||.::..|  |:|        ||:||...:.......|.|.:...:  :......
Zfish   379 RMPPPVVRVDTQQMNGMV--DDR--------GSESSTDMLDAESIHGSQTAARFSHILQKDAFLV 433

  Fly   137 PKSDIKIALKP----PPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDV----- 192
            .:|..|:::||    ||.|:|..:.  :.|.:..:.......   |.|...|..:..:.:
Zfish   434 FRSLCKLSMKPLADGPPDPKSHELR--SKVVSLQLLLSVLQG---AGPVFRTHEMFVNAIKQYLC 493

  Fly   193 -------TTKVTEVQRLPCDEPNT-------------------------ELISKRTEYKHTTITT 225
                   .:.|.||..|......|                         |..|...|:|...|.|
Zfish   494 VALSKNGVSSVPEVFELSLAIFLTLLSHFKVHLKMQIEVFFREIFLTILETSSSSFEHKWMVIQT 558

  Fly   226 TTRTLIVSR-PVELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEI--GTGGLFMEADPCSKNSL 287
            .||....:: .|::.:|.:.::.|        :|...|:::..::|  |..|..:...|..:.||
Zfish   559 LTRICADAQCVVDIYVNYDCDLNA--------ANIFERLVNDLSKIAQGRSGQELGMTPLQELSL 615

  Fly   288 PPP-------------PYIDDMRFIDDSSNSQSESER----NSNIHKTNKYTSKNNNNDSKRESQ 335
            ...             .:..|| :::.:..:....||    :|...|.:::.|...::.|..:|.
Zfish   616 RKKGLECLVSILKCMVEWSRDM-YVNPNLQANLGQERPAEGDSADVKLSEHLSSRRDSVSSLDST 679

  Fly   336 QSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMS 400
            .|            :.:...|.|:            .|..||:.:.:     |..:|
Zfish   680 VS------------SGVQQSQPDH------------PEQYEVIKQQK-----EIIEH-------- 707

  Fly   401 IGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVA 465
             |.:.||..||:|::||.|..:|...|:|:|.||.:.|.|:.|.:|::|||...||::|:..:|.
Zfish   708 -GIELFNKKPKRGLQYLQEQGMLGTSPEDIAQFLQQEERLDTTQVGEFLGENVKFNKEVMYCYVD 771

  Fly   466 LHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRY--CQLNPDIFTNTDTCYVLSFAIIM 528
            ..||.....|.|||.||..||||||||||||:||.||.||  |.....:|.:.||.|||:::|||
Zfish   772 RLDFCGKDFVSALRAFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIM 836

  Fly   529 LNTSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESI 572
            |.|.||:|.||:|.|.:|:|.||||||:..|||...|.|:|:.|
Zfish   837 LTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYDEI 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	86/178 (48%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
arfgef2	XP_002666513.2	PLN03076	16..1760	CDD:215560	167/629 (27%)
		DCB	38..213	CDD:292830
		Sec7_N	426..580	CDD:289549	27/158 (17%)
		Sec7	701..885	CDD:279680	88/194 (45%)
		DUF1981	1223..1304	CDD:286414

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820