Protein Alignment step and iqsec1a

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_001373523.1
• Gene: iqsec1a / 100334106
• ZFINID: ZDB-GENE-120813-2
• Length: 1000
• Species: Danio rerio
• Alignment Length: 662
• Identity: 165/662 - (24%)
• Similarity: 265/662 - (40%)
• Gaps: 143/662 - (21%)

  Fly     7 KRPSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVGCDGCV---------- 61
            :||.:.:..|.||:|.:.:........|||......||...:::...:.|.....
Zfish   176 QRPKLQHSQSILRKQAEEEAIKRSRSLSESYELSTDLQDKKVEMLERKYGGRFITRHAARTIQTA 240

  Fly    62 --------SLEFFQSESPESRRSNSTFYVN---------TQNVSSAVFKDNRQPLLERGSGSDSS 109
                    :.|..:|...|:|.|......|         .:.|.|:.|:..:..|:|..|
Zfish   241 FRHYQMNKNFERLRSSMSENRMSRRILLSNMRMQFSFEAPEKVHSSFFEGRQMSLMEESS----- 300

  Fly   110 PSSVCVRCSCNSITKSGDR----NETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKL 170
                    ...::.:.|::    .|.|......:|....|:.....:..|:|.....| .|...|
Zfish   301 --------HIGAMVQPGEKVPVILEAPETQNDLTDTITELEDTFSKQVKSLAESIDDA-LNCRSL 356

  Fly   171 APDSPPPASPTLSTQTVN--------------CSDVTTKVTEVQRLPCDEP-------NTELISK 214
            ..:...|.......|...              | |||..:.|.:..|..:|       :|:.:|.
Zfish   357 HKEEIQPEQTVCELQQKRELPQPDEHHRLDEIC-DVTLFIDEEELSPLVQPSSAESDQHTQSVSA 420

  Fly   215 RTEY--KHTTITTTTRT----------LIVSRPVELLLNENGEIIARRSPRKSRSNSLGRMLDVQ 267
            ..||  ....:.|:.|:          |.|..|| |.:....:..|..|.|..:.     ::..|
Zfish   421 SQEYWSMDANMDTSARSTPSLDYQSPKLCVDLPV-LTIEPPSDSSADASDRSEQG-----LVQTQ 479

  Fly   268 NEIGTGGLFMEADPCSKNSLP-----------PPPYIDDMRFIDDSSNSQSESERNSNIHKTNKY 321
            |..........|:|  |:.||           |..:...:..:..:.:.||:||.:.:....:..
Zfish   480 NVPKQTTAAPRANP--KHGLPARVPSLSGEEEPLRHRQVVSHLATNGSRQSKSESDFSDGDNDSI 542

  Fly   322 TSKNNNND---SKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQI--KDELCEVVSEM 381
            .|.:|:.|   |:..|.|.||                           |||.  ||       ..
Zfish   543 NSNSNSIDTINSESSSSQQNL---------------------------SKQTYHKD-------TR 573

  Fly   382 EALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIG 446
            .:.|.|.......:.:|..||...||..|:|||:||.|...:...|..|||||.:.:||::..||
Zfish   574 NSWDSPASSSDIMRKRQYRIGLNLFNKKPEKGIQYLTERGFIPDTPVGVAHFLLQRKGLSRQMIG 638

  Fly   447 DYLGEK-NDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNP 510
            ::||.: ..||.|||...|...||:.:.|.:|||:|....|:.|||||::|::|.|:||||..|.
Zfish   639 EFLGNRQKQFNRDVLDCVVDELDFSGMELDEALRKFQAQIRVQGEAQKVERLIEAFSQRYCICNH 703

  Fly   511 DI---FTNTDTCYVLSFAIIMLNTSLHNPSVK--DKPTVDQFISMNRGINNGGDLPRGLLESLYE 570
            |:   |.|.||.::|:||||:|||.:::|:||  .|..::.|:...||:::|.|:||.:|..:||
Zfish   704 DVVRQFRNPDTIFILAFAIILLNTDMYSPNVKIERKMKLEDFVKNLRGVDDGEDIPREMLVGIYE 768

  Fly   571 SIRTEPFKIPQD 582
            .|:.:..|..:|
Zfish   769 RIQKKELKTNED 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	79/185 (43%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
iqsec1a	NP_001373523.1	Sec7	587..775	CDD:396096	79/187 (42%)
		IQ_SEC7_PH	807..942	CDD:406773

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810